A&P 1: Integumentary System

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Skin Functions

Protect from invading bacteria. Holds in water and heat.

Epidermis

Outer layer of skin. Has five sub-layers.

Dermis

Second layer of skin. Has two sub-layers.

Hypodermis

Third layer of skin

Stratum Basale

Deepest layer of Epidermis. Single layer. Where mitosis takes places. Melanocytes, melanosomes, and Merkel cells.

Melanocytes

Cells that make melanin.

Melanosomes

Granules of melanin

Merkel cells

Docking station for nerve endings. Beacon for nerve signals.

Stratum Spinosum

Second deep layer of the Epidermis. Several layers. Keratinocytes, melanin granules, and Langerhan's cells.

Melanin Granules

UV shield for keratinocytes.

Langerhan's cells

Dendritic. Macrophages that activate the immune system.

Stratum Granulosum

Middle layer of Epidermis. 3-5 layers thick. Nuclei begins to disintegrate.

Stratum Lucidum

Clear band of cells. Found ONLY in thick Epidermis. Palms, soles of feet.

Stratum Corneum

Outer layer if Epidermis. 20 to 30 layers. No nuclei. Glycolipids from the cell matrix cause this layer to be waterproof.

Melanin

Skin Pigment. Yellow, Redish-brown, black. Protects DNA from UV radiation. Chemical layer of skin.

Carotene

Yellow/Orange pigment.

Hemoglobin

Red/Pink color. Caused by red blood cells in the dermis.

Moles

Accumulation of melanin

UV radiation

Destroys the body's folic acid stores.

Leathery skin

Caused by clumping of elastin fibers from excessive exposure to skin.

Erythema

Redness. Blood vessel dilation due to: blushing, fever, hypertension.

Pallor

Paleness. Blood vessels constrict due to: fear, stress, anemia.

Jaundice

Yellowing. Caused by a liver disorder.

Hematoma

Bruising. Due to blood escaping from the blood vessel and clotting beneath the skin.

Cyanotic

Bluish tent to mucous membrane. Due to poorly oxygenated blood: respiratory problem

Papillary Layer

Superficial layer of Dermis. Areolar loose connective tissue. Abundant in blood vessels, pain receptors, and Meissner's Corpuscles.

Meissner's Corpuscles

Touch receptor in the papillary layer of the dermis. Tactile disc for light touch.

Dermal ridges

Caused by dermal papillae. Has sweat glands along crest. Leads to the fingerprint on the epidermis.

Reticular Layer

Deepest layer of dermis. Made up of Collagenous Fibers (elastic & reticular).

Tension lines

Less dense areas of collagen. Surgeons use to follow with incisions.

Flexure lines

Near joints. Attaching to deeper layers.

Striae

Stretch marks. Tearing of the dermis.

Eccrine Glands

Simple, coiled, and tubular. Most abundant. Palms, soles, forehead. Simple Cubodial Epithelium. Secrete sweat for overheating, or emotional response.

Apocrine Glands

Armpit and anogenital region. Secretes sweat with fatty acids into ducts.

Sebaceous Glands

Found all over body except hands and feet. Secretes only sebum. Impedes H2O loss, bactericidal, lubricates and softens hair.

Medulla of the Hair.

Central core. Large cells separated by air cells.

Cortex of the Hair

Surrounds the medulla

Cuticle of the Hair

Single layer. Keratinized. Outside layer of the hair.

Hair Bulb

A knot of sensory nerves surround this on the hair.

Papillae

Dermal tissue that extends into bulbs. Contains capillaries for nutrients.

Alopecia

Natural thinning. In the 40s the hair is not replaced as fast.

Male Pattern Baldness

Genetic. Response to change in the body's testosterone levels.

Warts

Viral infection of the skin.

Psoriasis

Hereditary. Rashes on skin. Often triggered by stress/hormonal changes.

Superficial Burn

First Degree burn. A sunburn.

Partial Thickness Burn

Second Degree burn. Blisters. 3 to 4 weeks to heal.

Full Thickness Burn

Third Degree burn. New skin can only regenerate from the edge. Usually requires surgery and grafting.

Basal Cell Carcinoma

Least fatal skin cancer. Starts in Basal layer of Epithelium. Slowly spreads to other layers until removed.

Squamous Cell Carcinoma

Skin cancer. Starts in the Spinosum layer. Can metastasize to the lymph nodes if not removed.

Malignant Melanoma

Most fatal skin cancer. Starts in the melanocytes. Can metastasize to the lymph and blood.

Low pH of Skin

Works with the acid mantel to retard bacterial growth. Chemical layer of skin.

Bactericidal

Dermcidin. From sweat and sebum. Chemical layer of skin.

Defensins

Secreted by epithelium. Directly kills bacteria. Chemical layer of skin.

Pacinian Corpusclese

Tough receptor in dermis. For deeper pressure.

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