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5 Written questions

5 Matching questions

  1. type of genome of all viruses spread by animal vectors
  2. Negri bodies
  3. Why animal vector viruses are dangerous to humans
  4. Symptoms of hemorrhagic fevers caused by lassa, Ebola
  5. Mechanism of mosquito transmission
  1. a Eosinophilic cytoplasmic inclusion body found in nerves and characteristic of rabies
  2. b RNA
  3. c Severe hemorrhage due to viral cytopathic effect in the vascular endothelium
  4. d Humans have no natural resistance because they don't usually see these viruses
    -they are not the normal host
  5. e Mosquito bites its subject injecting a bit of saliva containing the virus into the blood bypassing the skin barrier

5 Multiple choice questions

  1. -Seen in Colorado tick fever
    -transmission pattern: small animals→ ticks→ other tics → back to small animals
    -humans are incidental
  2. -Encephalitis
    - fever with uremic syndrome
    -pulmonary syndrome
    -hemorrhagic fever
  3. Rabies
    sin nombre
  4. -Killed vaccine for humans
    -live attenuated vaccine for animals
    -vaccine recommended for high-risk people (veterinarians, postexposure)
    -rabies immunoglobulin use for postexposure prophylaxis (must must must be started before patient is symptomatic)
  5. Doesn't occur in cities because the viruses are maintained by transmission between animal and insect; humans are just incidental hosts
    -examples = yellow fever, WEE, VEE, lacrosse, West Nile

5 True/False questions

  1. Pathogenesis of Arboviruses-Introduced into the bloodstream by infected insects
    -viral replication in reticuloendothelial system in vascular epithelium
    -secondary viremia can seed target organs


  2. Urban cycle transmission patternMosquitoes to humans and back to mosquitoes
    -humans are considered endemic hosts


  3. dead end or incidental hostsThe incidence of infection is much higher than the number of people that develop clinical symptoms
    -for every person that develops West Nile encephalitis there are approximately 150 people who are infected


  4. arbovirus-Arthropod borne
    -can be transmitted by bloodsucking arthropods including tics, sand flies, and mosquitoes


  5. Human to human transmission1. Patient gets bitten by and in fact dead skunk, Fox, bat, raccoon, dog, cat
    2. virus replicates in muscle tissue at the site of the bite and spread to local nerve cells
    3. travels via retrograde transport to CNS and replicates in the gray matter virus
    4. virus will also spread to salivary glands via nerves


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