Hormone Regulation of Calcium

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The three most common hormones associated with calcium homeostasis.

Calcitonin stimulus

High blood calcium level

Calcitonin source

Thyroid gland (parafollicular glands)

Calcitonin target tissues

Bone, kidney, intestine

Calcitonin actions

Inhibition of osteoclast activity (decreased bone resorption)
Increased excretion of calcium in kidney
Inhibition of calcium absorption in intestine

Calcitonin goal

Decrease blood calcium level

Parathyroid hormone (PTH) stimulus

Low blood calcium level

Parathyroid hormone (PTH) source

Parathyroid gland

Parathyroid hormone (PTH) target tissues

Bone, kidney, intestine

Parathyroid hormone (PTH) actions

Stimulates osteoclast activity (increased bone resorption)
Decrease excretion of calcium in kidney
Stimulates calcium absorption in intestine
Promotes calcitriol (Vit. D) action

Parathyroid hormone (PTH) goal

Increase blood calcium level

Calcitriol (Active form of Vitamin D) stimulus

Low blood calcium level

Organ in which calcitriol is made

Kidney

Calcitriol actions

Stimulates osteoclast activity (increased bone resorption)
Decrease excretion of calcium in kidney
Stimulates calcium absorption in intestine

Calcitriol goal

Increase blood calcium level

Effectors that stimulate calcitriol production

PTH, low blood calcium

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