Hemostasis and coagulation- calvarez2
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calvarez2 Plus on February 21, 2012
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Term 1, Unified Exam 2, Margaret Anderson
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35 terms
Terms | Definitions |
|---|---|
 _____ is the process that stops bleeding from a damaged blood vessel | hemostasis |
| Hemostasis is the process that _____ | stops bleeding from a damaged vessel |
| Excessive bleeding and blood loss is called _____ | hemorrhage |
| Hemorrhage is the opposite of _____ | hemostasis |
| When a vessel is injured, processes are set in motion to _____ | form a clot |
| Clot formation is called _____ | coagulation |
| _____ is called coagulation | clot formation |
| A clot that is so large that it occludes a vessel is called a _____ | thrombus |
| Thrombus is _____ | a clot that occludes a vessel |
| A clot that is so unstable that it can be dislodged and occlude a vessel downstream is called _____ | embolus |
| embolus | A clot that is so unstable that it is dislodged and occludes a vessel downstream |
| Clot formation must be accomplished WHILE _____ | letting blood to continue to flow through the injured vessel during repair |
| When the wound to a vessel is repaired, a clot must be _____ | dissolved |
| T or F: Clotting and hemostasiscan maintain the integrity of a severed major artery | False: A tourniquet must be applied to prevent excessive bleeding |
| Functions of plasma proteins | Contribute to colloid osmotic (oncotic) pressure, defend against foreign invaders, participate in blood clotting, are carriers for hormones and cholesterol and ions, serve as signaling molecules and extracellular enzymes or cytokines |
| Function of Albumins | Major contributors to oncotic pressure of plasma; carriers of various substances |
| Organ source of Albumins | Liver |
| Function of globulins | clotting factors, enzymes, antibodies, carriers for various substances |
| organ source of globulins | liver and lymphoid tissues |
| function of fibrinogen | forms fibrin threads essential to blood clotting |
| organ source of fibrinogen | liver |
| function of transferrin | iron transport |
| organ source of transferrin | liver and other tissues |
| hematopoiesis | synthesis of blood cells |
| When does hematopoiesis begin? | Hematopoiesis begins at about the 3rd week of embryonic development and continues throughout life |
| 3 main types of blood cells: | Red blood cells, white blood cells, platelets |
| platelets AKA _____ | thrombocytes |
| **In primary hemostasis, formation of the platelet plug requires | collagen because collagen gets exposed and then everything else gets activated |
| **What other molecules besides collagen are involved in primary hemostasis | Integrins, platelet aggregating factors |
| **Timing | ... |
| mengiococcemia, niceria bacteria | ... |
| treatment for meningicoccemia | protein C |
| Chemical Factors involved in coagulation | ... |
| **plasminogen is incorporated into the clot, not _____ | plasmin |
| tPA is released by the _____ | damaged endothelium |
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