Immunohematology Antibody Chart

Created by RockFlemings37 

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Describes ABY class, clinical significance, reaction phases, enzyme effect, and other features of antibodies

Which ABYs are IgG?

-Rh (D, C, E, c, e)
-Kell
-Duffy
-Kidd
-S,s,U

Which ABYs are IgM?

-M,N
-P
-Lewis

Which phase(s) does Rh ABYs react?

-37C
-AHG

Which Rh ABY is the most antigenic?

Anti-D

Which phase(s) does Kell ABYs react?

AHG

Which ABY is the most antigenic next to Anti-D?

Kell

Which phase(s) does Duffy ABYs react?

AHG

Which ABY is associated with malaria?

Duffy

Which phase(s) does Kidd ABYs react?

AHG

Which ABY is associated with delayed transfusion reactions?

Duffy

Which phase(s) does M,N ABYs react?

-Initial Spin
-37C
-AHG

Which phase(s) does S,s,U ABYs react?

AHG

Which phase(s) does Lewis ABYs react?

-Initial Spin
-37C

Which ABY are lost during pregnancy?

Lewis

Which ABY is associated with African Americans?

Lewis b

Which AGNs are absorbed onto RBCs from plasma (rather than being produced by the RBCs)

Lewis

Which phase(s) does "P" ABYs react?

Initial Spin

Which phase(s) does "I" ABYs react?

Initial Spin

Which cold ABY is associated with M. pneumoniae infection?

Anti-I

Which cold ABY is associated with Infectious Mononucleosis?

Anti-i

What is the enzyme effect on Rh ABYs?

Enhanced

What is the enzyme effect on Kell ABYs?

No Effect

What is the enzyme effect on Duffy ABYs?

Destroyed

What is the enzyme effect on Kidd ABYs?

Enhanced

What is the enzyme effect on MNS ABYs?

Destroyed

What is the enzyme effect on Lewis ABYs?

No Effect

What is the enzyme effect on "P" ABYs?

No Effect

What is the enzyme effect on "I" ABYs?

No Effect

Which ABYs are enhanced by enzymes?

-Rh
-Kidd

Which ABYs are destroyed by enzymes?

-Duffy
-MNS

Which ABYs are clinically significant?

IgG

Which ABYs are NOT clinically significant?

IgM

Which ABYs can be neutralized?

-Lewis a
-Lewis b
-P1

Which enzymes are used to enhance or destroy ABYs on a panel?

-Papain
-Ficin

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