Maintaining relatively constant conditions and internal balance. Basically, health.
fluid within a cell
Most of the body's fluids are found ______ the cell.
fluid outside the cell
- includes intravascular and interstitial fluid
Fluid in blood vessels in the form of plasma or serum
- part of extracellular fluid
Fluid surrounding cells, including lymph
- part of extracellular fluid
_____ makes up the largest portion of body weight.
Fluid separated from other fluids by a cellular barrier and consists of cerebrospinal, pleural, gastrointestinal, intraocular, peritoneal, and synovial fluids.
Transcellular fluid is less than __% of the body's fluids.
percentage of body water _________ with age.
elderly, obese, babies
Who is most at risk for fluid imbalances?
functions of water
- transportation of nutrients, electrolytes, and oxygen to the cells
- excretion of waste products
- regulation of body temperature
- lubrication of joints and membranes
- medium for food digestion
Substance that develops an electrical charge when dissolved in water
a particle that is electrically charged (positive or negative)
substance that is dissolved
muscle contraction, nerve impulses
positive and negative charges are essential for ______ ___________ and _____ ________.
a positively charged ion
a negatively charged ion
Chloride, bicarbonate, and phosphate are examples of ______.
Sodium, potassium, calcium, and magnesium are examples of _______.
most abundant electrolyte, primary electrolyte in extracellular fluid, cation
functions of sodium (Na)
- major role in regulating body fluid volumes
- muscular activity
- nerve impulse conduction
- acid-base balance
- effects serum osmolality
found mainly in the intracellular fluid, the major intracellular cation
functions of potassium (K)
- skeletal and smooth muscle contractions
- especially important in the heart
- important in maintaining fluid osmolarity and volume within the cell
- essential for normal membrane excitability - a critical factor in transmitting nerve impulses
- needed for protein synthesis, for the synthesis and breakdown of glycogen, and to maintain plasma acid-base balance
an extracellular anion that is usually bound with other ions, especially sodium or potassium
functions of chloride (Cl)
- regulate osmotic pressure between fluid compartments
- assist in regulating acid-base balance
Cation that is usually combined with phosphorous to form the mineral salts of the bones and teeth, ingested through the diet and absorbed through the intestine
- 99% concentrated in the bones and teeth
- 1% in the extracellular fluid
functions of calcium (Ca)
- promotes transmission of nerve impulses
- helps regulate muscle contraction and relaxation
a cation found in bone (50% - 60%), intracellular fluid (39%-49%), and extracellular fluid (1%)
functions of magnesium (Mg)
- plays a role in the metabolism of carbohydrates and proteins
- storage and use of intracellular energy
- neural transmission
- important in heart, nerve, and muscle function
Solutes that do not carry an electrical charge
examples of nonelectrolytes
- carbon dioxide
selectively permeable membranes
Allow only certain molecules to pass through
- separate fluid compartments and control movement of water and certain solutes
- maintain unique composition of each compartment of the body while allowing transport of nutrients and wastes to and from cells
- kind of like a collander or fish net, straining system
osmosis, diffusion, filtration, active transport
The four primary ways fluids and electrolytes shift or transport between compartments include: _______, _________, __________, and ______ _________.
Movement of water across a membrane from an area of lower concentration to an area of high concentration
pressure that must be applied to prevent osmotic movement across a selectively permeable membrane
process by which molecules tend to move from an area where they are more concentrated to an area where they are less concentrated
- like osmosis, only with solutes instead of water and goes from high concentration to low concentration
- the warmer the temp, the faster the movement
carrier proteins transport substances from and area of lower concentration to an area of equal or greater concentration
- requires expenditure of energy (uses ATP)
transfer of water and solutes through a membrane from an area of high pressure to an area of low pressure
concentration of solution determined by number of dissolved particles per kg of water
- reflects hydration status
- measured by serum and urine
- solutes measured: mainly urea (BUN), glucose, and sodium
- basically just means concentration
- when you see osmolality or osmolarity just think "concentration" :)
concentration of a solution determined by the number of dissolved particles per liter of a solution
- usually talking about IV fluids whereas osmolality is usually referring to the pt's serum
- pretty much the same thing as osmolality
- moving fluid out of an artery in the capillary bed
- moving fluid into a vein in the capillary bed
- blood plasma entering the kidney via the renal artery is delivered to the glomerulus
- about 20% of plasma is filtered into the glomerular capsule
- most remaining plasma leaves the kidney through the renal vein
- filtrate then moves through the tubules where it is transformed into urine by tubular reabsorption and secretion
tubular reabsorption (kidneys)
Process by which most of the glomerular filtrate is returned to circulation
- water and selected solutes move from the tubules into the capillaries
- wast products remain in tubules for excretion, whereas most water and sodium is reabsorbed into the blood stream
- adjusts volume and composition of the filtrate; prevents excessive fluid loss through kidneys
tubular secretion (kidneys)
The last phase in the work of the kidneys in which the filtrate is transformed into urine
- various substances: drugs, hydrogen ions, potassium ions, creatinine, and histamine pass from the blood into the tubules
- process eliminates some excess substances to maintain fluid and electrolyte balance as well as metabolic waste products
In healthy adults, 24-hour fluid I&O should be approximately _____.
The usual adult urine volume is between __-__ liters per day or __ ml/kg of body weight per hour.
We lose approximately ___-___ml of water through evaporation in the lungs every day.
We lose approximately ___-___ml of water daily in the GI tract.
The loss of water not noticeable by a person, such as through evaporation from the skin and exhalation from the lungs during breathing.
- unmeasurable water loss
water losses that are measurable, such as urinary output and wound drainage
30, 55-65, 25, 65
Unless contraindicated, fluid requirements for older adults, based on ideal body weight, are __ml/kg for ages __-__ and __ml/kg for __ years and older.
medical conditions effecting water balance
- diarrhea, vomiting
- NG suction
- wound drainage
- mechanical ventilation
- uncontrolled diabetes, diabetes insipidus
determines if patient has conditions that contribute to fluid or electrolyte imbalances
"red flag" assessment findings
complaints of fatigue, palpitations, dizziness, edema, muscle weakness or cramps, dyspnea, and confusion may be associated with fluid imbalances.
One liter of water is equal to __.__lbs or __kg.
respirations are _________ effected by electrolyte changes.
BP is directly related to blood ______.
______ is one of the best ways to assess fluid imbalance.
_____ characteristics also give clues to fluid balance.
- clear, pale in a healthy person suggests the excretion of excess water, whereas darker, concentrated indicates the kidneys are retaining water
Dry, flushed skin can mean?
Pale, cool, clammy skin can mean severe fluid volume deficit that occurs with _____.
Moist, edematous tissue is seen with ______ fluid volume.
fluid volume deficit
Soft eyeballs and sunken eyes may indicate what?
fluid volume excess
Puffy eyelids and fuller cheeks suggest what?
sternum, thighs, forehead
Skin turgor is measured by pinching the skin over the _______, the inner aspects of the ______, or the ________.
fluid volume excess
Edema (especially pitting) is an indication of what?
longitudinal, deficit, smaller, red, swollen
In well person, the tongue has one ____________ furrow. Fluid volume _______ causes addition longitudinal furrows, and the tongue is _______. Sodium excess causes the tongue to appear ___ and _______.
deficit, mouth breathing
A dry mouth may be the result of fluid volume _______ or _____ _________.
appearance of the jugular veins in the neck and the veins in the hands can suggest either a fluid volume _______ or ______.
- oral fluids
- parenteral fluids
- irrigation fluids
- solid foods
measurable output (sensible loss)
- drainage from body cavities
non-measurable output (insensible loss)
- vaporization through lungs
normal Na and serum osmolality
decreased Na and serum osmolality
increased Na and serum osmolality
Normal fluid intake is about ____-____ml/day.