More more Host Defense Block 2
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30 terms
Terms | Definitions |
|---|---|
 which bacteria cause gastroenteritis via contaminated food/water? | ETEC EHEC salmonella Y. entercolitica |
| which bacteria cause gastroenteritis via person-to-person transmission? | EPEC Shigella |
| which two organisms produce urease? what does urease do? | P. mirabilis and H. pylori converts urea to carbon dioxide/bicarbonate and ammonia |
| what enzyme on a dipstick of a urinalysis indicates a UTI? | leukocyte esterase |
| which STD presents with very different symptoms for men and women? What are they? | N. gonorrhoeae Men: painful urination, pus from urethra Women: often asymptomatic, pelvic inflammatory disease |
| 3 characteristics of hemolytic-uremic syndrome | acute renal failure, thrombocytopenia, microangiopathic hemolytic anemia |
| sepsis + petichiae = which pathogen? | n. meningitidis |
| which bacteria is found in colder climates/ during colder months of the year? | yersinia |
| ActA | Listeria |
| describe the toxins from Pseudomonas aeruginosa | T3SS ExoT, ExoS, ExoY Alters signaling pathways in host phagocytic cells ExotoxinA (an A-B toxin) |
| chronic granulomatous disease pathogen | Burkholderia cepacia |
| "thumb sign" on an xray is indicative of what? | epiglottitis |
| prior carbapenem treatment can predispose someone to infection with ___ | stenotrophomonas |
| whooping cough caused by which organism? | bortadella pertussis |
| how to diagnose Legionella? | urine antigen test intracellular pathogens in human alveolar macrophages; prevent lysosome fusing with phagosome. |
| if recurrent infections with neisseria meningitidis, what do we suspect? | a complement deficiency |
| if otitis media in kids, think which organism | H. influenzae non-typeable (non-encapsulated) |
| for which pathogen do we see the highly pro-inflammatory LOS instead of LPS? | Neisseria (meningitidis and gonorrhoeae) AND Haemophilus influenzae |
| don't treat H. influenzae with ____ | beta-lactams |
| otitis externa, consider which pathogens? | pseudomonas staph aureus |
| stenotrophomonas always always always resistant to ____ treat with what instead? | carbapenems TMP-SMX |
| ceftriaxone a good choice for what diseases? | hospital acquired pneumonia bacterial meningitis gonorrhea (+doxycycline for possible chlamydia) brain abscessess (anaerobic) |
| what is Fitz-Hugh Curtis syndrome, and what is it caused by? | RUQ pain, abnormal liver function test, fever caused by gonorrhea and chlamydia |
| what are the 3 things to remember with epiglottitis? | dysphagia, drooling, distress |
| what are the aerobic, non-fermenting gram (-) rods? | pseudomonas, burkholderia, stenotrophomonas, acinetobacter |
| what are the 4 fastidious, mucosal gram (-) rods? | bortadella, legionella, neisseria, haemophilus |
| ecthyma granulosum; what does it look like, what is it associated with? | rounded skin lesions with central necrosis pseudomonas and others |
| treat pertussis with ____? | macrolides |
| asplenia predisposes people to infections by what? | encapsulated organisms |
| Lemierre's syndrome- where and which pathogen? | lateral pharyngeal space fusobacterium; causes septic thrombosis of the IJV --> bactermia and septic pulmonary embolism |
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