Chapter 17 : Blood

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Human Anatomy and Physiology 8th Edition Marieb

All of the following can be expected with polycythemia except ________.

low blood viscosity

A lack of intrinsic factor, leading to a deficiency of vitamin B12 and large pale cells called macrocytes, is characteristic of ________.

pernicious anemia

Which of the following is not a phase of hemostasis?

fibrinolysis

Blood is a ________.

suspension

What is the average normal pH range of blood?

7.35-7.45

James has a hemoglobin measurement of 16 g/100 ml blood. This is ________.

within normal range.

Which of the following is true about blood plasma?

It is about 90% water.

Thromboembolic disorders ________.

include embolus formation, a clot moving within the circulatory system

Sickling of red blood cells can be produced in those with sickle-cell anemia by ________.

travel at high altitude and vigorous exercise

Place the following in correct developmental sequence:
1. reticulocyte
2. proerythroblast
3. normoblast
4. late erythroblast

2, 4, 3, 1

The slowest step in the clotting process is ________.

formation of prothrombin activator

Which of the following might trigger erythropoiesis?

hypoxia of EPO-producing cells

Complications of aplastic anemia generally do not include ________.

increase of leukocytes as a result of erythrocyte loss

Which blood type is called the universal donor?

O

The most abundant plasma protein is ________.

albumin

Hemorrhagic anemias result from blood loss.

True

A condition of leukocytosis indicates over 11,000 white blood cells per cubic millimeter in the blood.

True

Myelocytic leukemia involves a cancerous condition of lymphocytes.

False

Diapedesis is the process by which red blood cells move into tissue spaces from the interior of blood capillaries.

False

Basophils increase in number when parasitic invasion occurs.

False

Platelets ________.

stick to the damaged area of a blood vessel and help seal the break

Select the correct statement regarding blood cell formation.

Red marrow is the main site of blood cell formation throughout adult life.

When can erythroblastosis fetalis not possibly happen in the child of an Rh negative mother?

if the father is Rh-

Which of these is not a normal plasma protein?

Thromboplastin

As red blood cells age ________.

membranes "wear out" and the cells become damaged

What organ in the body regulates erythrocyte production?

Kidney

The special type of hemoglobin present in fetal red blood cells is ________.

Hemoglobin F

An individual who is blood type AB negative can ________.

receive any blood type in moderate amounts except that with the Rh antigen

Which of the following is a protective function of blood?

maintenance of body temperature

No visible cytoplasmic granules are present in ________.

monocytes

Which of the following is not a cause of bleeding disorders?

excess secretion of platelet-derived growth factor (PDGF)

Which of the statements below is an incorrect or false statement?

Blood typing for the Kell, Lewis, and Duffy factors is always done before a blood transfusion.

Which of the following is a regulatory function of blood?

maintenance of normal pH in body tissues

All of the following conditions impair coagulation except ________.

vascular spasm

Which of the choices below is the parent cell for all formed elements of blood?

pluripotent stem cell (hemocytoblast)

Each heme contains an atom of iron and can transport one molecule of oxygen.

True

The immediate response to blood vessel injury is clotting.

False

Positive chemotaxis is a feedback system that signals leukocyte migration into damaged areas.

True

All lymphocytes are leukocytes, but not all leukocytes are lymphocytes.

True

Leukopenia is an abnormally low number of leukocytes.

True

Fred's blood was determined to be AB positive. What does this mean?

There are no antibodies to A, to B, or to Rh antigens in the plasma.

When neither anti-A sera nor anti-B sera clot on a blood plate with donor blood, the blood is type ________.

O

Which sequence is correct for the following events?
1. fibrinogen → fibrin
2. clot retraction
3. formation of thromboplastin
4. prothrombin → thrombin

3, 4, 1, 2

Which of the following is a pivotal molecule associated with the external surfaces of aggregated platelets and is involved in the intrinsic and extrinsic mechanisms of blood clotting?

PF3

Which of the following is characteristic of all leukocytes?

They are nucleated.

Blood volume restorers include all of the following except ________.

packed cells

The slowest step in the clotting process is ________.

formation of prothrombin activator

Sickling of red blood cells can be produced in those with sickle-cell anemia by ________.

travel at high altitude and vigorous exercise

Which of the following is a regulatory function of blood?

maintenance of normal pH in body tissues

The special type of hemoglobin present in fetal red blood cells is ________.

hemoglobin F

What organ in the body regulates erythrocyte production?

kidney

Blood is a ________.

suspension

A lack of intrinsic factor, leading to a deficiency of vitamin B12 and large pale cells called macrocytes, is characteristic of ________.

pernicious anemia

An individual who is blood type AB negative can ________.

receive any blood type in moderate amounts except that with the Rh antigen

No visible cytoplasmic granules are present in ________.

monocytes

The RBC "graveyard" is the liver.

False

A person with type B blood could receive blood from a person with either type B or type O blood.

True

Hemoglobin is made up of the protein heme and the red pigment globin.

False

The process of fibrinolysis disposes of bacteria when healing has occurred.

False

White blood cells are produced through the action of colony-stimulating factors.

True

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