Rickettsiae and Spirochetes

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Created by:

bjtravis  on March 3, 2012

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hooahmedicarmyhooah

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Rickettsiae and Spirochetes

Rickettsial Disease
obligate intracellular parasites, suseptible to tetracyclines, Trans. by arthropods (lice, ticks, flea)
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Definitions

Rickettsial Disease obligate intracellular parasites, suseptible to tetracyclines, Trans. by arthropods (lice, ticks, flea)
Rickettsial Triad Fever, HA, rash (tache noire-scab like lesion w/ surrounding redness, cigarette burn)
Weil-Felix Test used to diagnose typhus or spotted fever
RMSF causative organism Rickettsia rickettsi
RMSF tick bite from hard shell tick (wood, dog, Lone-star), fever, HA, rash start peripherally (soles and plams), petichiae, fever before rash
African tick bite fever typical signs, inoculation eschars (cigarette burns)
Epidemic Typhus louse borne, FLS, macular rash(begins on trunk), cold climates w/ overcrowding
Brill-Zinsser typhus recurrence later in life
Murine/Endemic Typhus Rat fleas, rarely fatal, like Epidemic Typhus but milder
Epidemic Typhus Tx Doxy, Lindane powder
Tsutsugamushi Disease (scrub typhus) mite born(chiggers), FLS, lesion at site (becomes toche noire, cigarette burn), acute hearing loss
Tsutsugamushi Disease (scrub typhus) drugs Doxy (Z-pack in SE asia)
Q-Fever organisms are transmitted by contact with infected animals and animal products, unpasteurized milk, ticks, inhalation of aerosolized infected dust.
Sudden fever, chills, severe headache, malaise, myalgias, a non-productive cough, interstitial pneumonitis
NOTE: There is no rash
Spirochetal Infections Lyme disease, Leptospirosis, Relapsing fever, rate bite fever
Lyme Disease Deer tick, FLS, Neuro (Bell's Palsey), Erythema Migrans(bull's eye rash), common in U.S.
Leptispirosis(Weil's Disease) animal urine found fresh water, jaundice, signs of renal failure, hemorrhagic petechial rash, and aseptic meningitis. Conjunctivial suffusion = "injected" conjunctiva = "uniformly reddened" conjuntiva, FLS come and go
Spirochetes Microscopy dark field examination
Relapsing fever (tick, recurrent, or famine) fevers that come and go, from lice or ticks, N/V, jaundice
Rat bite fever rodent bite or contaminated water/milk, FLS w/ red and dusky maculopapular rash on truck and extremities
Rat bite fever DOC amoxicillin (DOC for animal bites)

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