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6 Written Questions

6 Multiple Choice Questions

  1. Cytotoxic
    Immune system identifies a normal part of the body as foriegn
    Causes- hemolytic transfusion reactions, IgG or IgM to cell-bound antigen
    Types- Goodpastures, Pernicious anemia, myasthenia gravis, thrombocytopenia
  2. Hyper-responsivenes (allergies, aunto-immune DO, Reaction to organ/tissue transplant)
    Impaired Immune Response (AIDS, HIV, Immunodeficieny DO)
  3. Immune complex (IgM & IgG)
    Circulating immune complexes deposited in body tissue
    Local inflammation & cell wall damage
    *persistent infections- edocarditism acute glomerulonephritis
    *Auto antibodies- rhematoid arthritis, systemic lupis
  4. Measures amount of IgE directed towards specific antigens
  5. IgE mediated hypersensitivity
    An allergen interacts with IgE bound to mast cells
    Histamine released
    If its potent-sytemic reactions
  6. Detects the presence of circulating immune complexes in type II hypersensitivity response
    Useful in autoimmune DO

6 True/False Questions

  1. AnaphylaxisVasodilation
    Increased cap permeability
    Smooth muscle contraction
    Bronchial constriction

          

  2. Direct Coombs TestDetects presense of circulation antibodies against RBC
    Normal to not have agglunation
    Part of cross & match
    (Blood & trasnfusion blood mixed-reaction??)

          

  3. Type IVCell mediated, delayed hypersensitivity
    T-cells sensitized to prev antigen
    Sensitized t-cells initiate inflammatory response
    Damage to surrounding tissue
    *TB skin test, contact dermatitis, graft vs host, transplant rejection

          

  4. Symptoms of AnaphylaxisSense of foreboding
    Light headed
    Itchy palms or scalp
    Hives
    Angioedema of face, lips, tongue, feet, or genitals
    Laryngeal edema with impaired breathing
    Bronchial constriction
    Air hunger
    Stridor
    Wheezing
    Barking cough

          

  5. Indirect Coombs TestDone if + indirect coombs or transfusion reaction occured

          

  6. Classification of Hypersensitivity ReactionsType I- anaphylactic
    Type II- Cytotoxic
    Type III- immune complex-mediated
    Type IV- Delayed
    Latex
    *Or immediate, delayed, anaphylactic, contact

          

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