Cardiovascular System
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35 terms
Terms | Definitions |
|---|---|
refers to the stoppage of bleeding | hemostasis |
vascular spasm, platelet plug formation, coagulation | three mechanisms to prevent blood loss |
vascular spasm | mechanism when blood vessels are damaged, the circulatory arranged smooth muscle in its wall contracts immediately, reduces loss for up to several hours |
platelet plug formation | mechanism when the damaged surface interrupts the smooth epithelial surface of the vessel and is likely to expose collagen to which platelets immediately stick, rather quick, reduces blood loss until clot can be formed |
serotonin thromboxane | platelets release two vasocostrictors: |
coagulation | mechanism when blood loses its fluid qualities and becomes a jell consisting of network insoluable protein fibers called fibrin where elements of blood are trapped |
liver | most clotting factors are synthesized in the .. and released into plasma |
TF or thromboplastin | released from damaged tissue cells |
fewer | an extrinsic pathway has... steps than an intrinsic pathway, and occurs rapidly |
tissue factor | known as thromboplastin or coagulation facter III |
extrinsic | tissue factor leaks outside of blood vessels and initiates the porduction of prothrombinase |
intrinsic | pathway that is more complex, and is much slower, requiring several minutes |
intrinsic | pathway that activators are in direct contact with blood |
collagen, phospholipids | if epithelial cells become roughened, or damaged, blood can come into contact with ... in the surrounding basal lamina. trauma can cause harm to platelets, releasing... . factor x is stimulated and combines with factor v to form prothrombinase |
x, v | factor .. combines with... to form prothrombinase |
common pathway insoluable | prothrombinase + Ca ions catalyze the formation of prothrombin to thrombin, then fibrinogen into fibrin threads, which are... |
the same | the steps in clotting after prothrombinase is formed is ... |
factor XIII | strengthens and stabalizes fibrin threads for a more sturdy clot |
factor XIII | occurs in plasma, released by platelets formed in the clot |
vitamin k | normal clotting depends on ... |
prothrombin | factorII is... |
II, VII, IX, X | four clotting factors produced by the liver |
vitamin k | normally produced by the bacteria the inhabit the large intestine |
clot retraction or syneresis | consolidation or tightening of a fibrin clot |
pulls damaged ends together | as a clot retracts, |
platelets | normal clotting depends on an adequete number ot platelets |
fibrinolytic system | provides checks and balances so that clotting doesnt get out of hand, also dissolves clots in site once damaged is repaired |
fibrinolysis, plasminogen | dissolution of a clot, when a clot is formed a plasma enzyme called... is incorperated into the clot |
plasmin | both body tissues and blood contain substances that can activate plasminogen into ... |
anemia | condition in which oxygen carrying compacity of blood is reduced |
iron deficiency | anemia due to inadequent supply of iron, resulting is deficient hemoglobin |
pernicious | anemia that the insufficient hemopoiesis that results from the inability of the stomach to prosuce intrinsic factor, needed for b12 absorbtion |
hemerragic | anemia due to excessive loss of RBCs due to hemmerage |
hemolitic | anemia when RBCs become mishapen causing the outer membrane to rupture prematurly |
aplastic | anemia as the result of faulty bone marrow is replaced by fatty tissue and fibrous tissue. causes are excessive x rays, drugs used for cancer, benzene, antibiotics |
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