Chromosomes coil and sister chromatids become apparent; Nuclear structures begin to disappear
Mitotic spindle begins to form. Critical for moving chromosomes during mitosis; has two focal points.
Nuclear envelope begins to break down; Mitotic spindle enters nuclear region. Spindle microtubules attach to centromeres via kinetochore complex (Sister chromatids become attached to opposite poles of the spindle).
Nuclear envelope absent; Action of mitotic spindle aligns sister chromatids at metaphase plate
Centromeres separate ("disjunction"); Daughter chromosomes move toward poles. Cytokinesis begins
Daughter chromosomes complere movement to poles; chromosomes uncoil, nuclear envelope reforms. Spindle microtubules disappear.