What organs do normal microbiota NOT colonize in the digestive system?
DES: duodenum, esophogus, stomach
Most common normal microbiota of MOUTH?
Normal microbiota of predominate in lower intestine, colon?
Bacteroides, Lactobacillus, Escherichia, Candida other enterobacteria
Primary benefit of (normal) microbiota? (and other uses)
Inhibit pathogens by microbial antagonism; provide vitamin to host, produce flatus and convert some substances to toxins/carcinogens
Mouth bacterias that destroy enamel of teeth/create cavities?
Streptococcus mutans, Lactobacillus
PG movie is about poor mona's gingivitis
Loss of bone, tooth loss, increased inflammation
What causes peptic ulcers?
Helicobacter pylori (peptic ulcers) how does it infect?
Bacterium burrows through mucus lining of stomach, allowing entry to stomach acid, dissolving a hole and causes pain
Symptoms of Bacterial gastroenteritis?
Nausea, vomiting, cramping, often fever
Examples of bacterial gastroenteritis?
Cholera, traveler's diarrhea, shigellosis, campylobacter, gastroenteritis, salmonellosis
Most common cause of diarrhea (in US)?
Traveler's Diarrhea most commonly caused by?
Shigellosis does what?
Multiplies in cell's cytosol
Vibrio cholerae/salmonellosis pathogenesis
VC too much energy, fights in water leads to dehydration
What does E. coli do?
produces Shiga-like toxin (related to Shiga toxin "Shigella" -> shigellosis) and enterotoxins to cause FATAL gastroenteritis
What does salmonella result in?
salmonellosis (dirty eggs) typhoid fever (dirty water, food)
What is bacterial food poisoning infection aka?
What's misleading about bacterial food poisioning
bacterial intoxication where TOXIN is PRESENT/ACTIVE, but BACTERIA NOT
Staphylococcal food poisoning?
a common intoxication produced by enterotoxins of STAPHYLOCOCCUS AUREUS
Fever blisters/cold sores/oral herpes caused by?
Herpes simplex virus 1
infection of mumps virus of parotid salivary glands of children
Viral gastroenteritis vs Bacterial Gastroenteritis: what's milder?
Viral gastroenteritis is milder
Viral gastroenteritis leading causes?
(Vanessa GAS CAR) calcivirus (norovirus), astrovirus, rotavirus
Black and yellow (dark urine and jaundice), vomiting, nausea, weight loss
inflammation of liver, "A,B,C,Delta,E"
HBV, HCV, HDV pathogenesis?
Sexually transmitted or contaminated needles
Hepa A, E (HAV, HEV) pathogenesis
What is Giardiasis?
severe, foul-smelling "rotten egg" watery diarrhea, a common resident of waterways throughout US
"Beaver fever" pathogen?
Diarrhea, cramping, nausea
3 forms of Amoebiasis?
Luminal amebiasis, amebic dysentery, invasive extra intestinal amebiasis
Significant diarrheal disease
Invasive extra intestinal amebiasis?
potential FATAL disease where amoebae invade body and form necrotic lesions in various organs
Beef tape worm pathogen? Pork tapeworm pathogen?
Beef: Taenia saginata
Pork: Taenia solium
Enterobius vemicularis; nematode
male and female worm male in intestinal tract; female crawls out to anus and lay eggs, leading to intense peri-anal itching
Common childhood parasite?