Cell Division
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Created by:
jdummett16 on March 25, 2012
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Part 2
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15 terms
Terms | Definitions |
|---|---|
 Internal Signals of Cell cycle | The stages follow one another in normal sequence and that each stage is properly completed before the next stage |
| External Signals | Tell whether the cell divides or not |
| Cyclins | Increase and decrease as the cell cycle continues |
| The first checkpoint of G1 | The cell to determine whether conditions are favorable to begin the cell cycle |
| DNA damge | can stop the cell cycle at the G1 checkpoint |
| Mammalian cells | the p53 protein stops at the cycle of G1 checkpoint when DNA is damaged |
| Cell Cycle stops at the G2 checkpoint | if DNA finished replicating |
| If repair is not possible | apoptosis occurs |
| Checkpoints are critical | For preventing cancer |
| Carcinogenesis | The development of cancer, multi - stage involves disruption of cell division and behavior |
| Initiation of cancer | A mutation occurs in the DNA of the cell |
| Proto - oncogenes | Encodes proteins that promote the cell cycle and prevent apoptosis |
| Tumor suppressor genes | Encode proteins that stop the cell cycle and promote apoptosis |
| Oncogenes | Cancer causing genes |
| Tumor suppressor genes mutate, | Their product no longer inhibit the cell cycle |
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