Cholinergic Therapeutic Uses

15 terms by iDoRX 

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bethanechol

GI bladder stimulant, xerostomia (dry mouth)

methacholine (Provocholine)

asthma diagnosis

direct cholinergic choline esters and congeners

ACh, methacholine, carbachol, bethanechol

direct cholinergic alkaloids

muscarine, pilocarpine

indirect reversible cholinesterase inhibitors

physostigmine (eserine), neostigmine, pyridostigmine

physostigmine (eserine)

reversible AChase inhibitor, no quat. structure, penetrates into CNS

neostigmine

Dx: myasthenia gravis

pyridostigmine

protection against organophosphate gases, Tx: myasthenia gravis

CNS selective cholinesterase inhibitors

donepezil, tacrine (Cognex), rivastigmine, galantamine

Indirect irrever. AChase inhibitors

organophosphates, phosphate esters, echothiophate

pesticides

parathion, malathion

war gases

tabun, soman, sarin

irrever. AChase inhibitor antidote

atropine + pralidoxime (2-PAM)

slowly reversible AChase inhibitors

sevin (Carbaryl)

slowly rev. Achase inhibitor antidote

atropine + support

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