__________ ___________is the regulation of an enzyme or other protein by binding an effector molecule at the protein's allosteric site (that is, a site other than the protein's active site)
In addition to their function in respiration, the lungs also:
Alter the pH of blood by facilitating alterations in the partial pressure of carbon dioxide
Filter out small blood clots formed in veins
Filter out gas micro-bubbles occurring in the venous blood stream such as those created during decompression after underwater diving .
Influence the concentration of some biologic substances and drugs used in medicine in blood
Convert angiotensin I to angiotensin II by the action of angiotensin-converting enzyme
May serve as a layer of soft, shock-absorbent protection for the heart, which the lungs flank and nearly enclose.
Immunoglobulin-A is secreted in the bronchial secretion and protects against respiratory infections.
Maintain sterility by producing mucus containing antimicrobial compounds. Mucus contains glycoproteins, e.g. mucins, lactoferrin, lysozyme, lactoperoxidase. We find also on the epithelium Dual oxidase 2 proteins generating hydrogen peroxide, useful for hypothiocyanite endogenous antimicrobial synthesis. Function not in place in cystic fibrosis patient lungs.
Ciliary escalator action is an important defence system against air-borne infection.The dust particles and bacteria in the inhaled air are caught in the mucous layer present at the mucosal surface of respiratory passages and are moved up towards pharynx by the rhythmic upward beating action of the cilia.
Provide airflow for the creation of vocal sounds.