Cc breast cancer
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16 terms
Terms | Definitions |
|---|---|
 Breast ca. Physical mf.asymmetrical vs symmetrical eczema in the breast In a NON lactating fem | Asymmetric. Symmetrical eczema -Paget 's ds of breast - Allergic eczema |
| Breast ca If you see Mastitis in non lactating vs lactating fem what is the next step | Non lactating Lactating mastitis Do w/u for infl BR Ca. Likely cellulitiis |
| BR CA screening. 3 guidelines. For screening -MMG | ACP ACP. USPSTF -At 40. Q1yr ?50-74 40-49 q 2y optional (til women good 50-74 q2yrs health) -CBE > 40 q1yr. ? Insuf data ( 20-39 q3yr) |
| BR CA. Screening. What are indication for MRI of the breast in screening (5) | PH. FH -BRCA1, or 2 / 1 DR w BRCA in untested pt -TP53 or PTEN mut. /. or 1DR w.... -LTR >20%. X -radiation chest 10-30yo. X |
| BREASt CA. W/u. 4 steps | 1. MMG 1st, +/- u/s, +/- MRI 2. FNA 3. Determine receptors E/P, and HER2/neu 4. Tx |
| BREAst ca w/u. Suspicious findings on MMG (3) | A rchitecture distortion B order irregular w densities C luster of irregular calcifications |
| BR CA w/u. What is the use for u/s of the breast | 1. To determine if lesion is cystic or solid |
| BR CA. W/u what is the next step when simple cyst and solid tm ID by u/s. | Simple cyst. Solid tm -Do fluid aspiration. - Refer for bx |
| Breast. Carcinoma in situ (non-invasive). Cl CRT of 2 types. | LCIS. DCIS!! -Is a marker of -evolve in invasive CA Invasive CA. at 1% /yr -freq B/L. -has distict microcalc -mult lobular on MMG, and 1 lobule X. -low, med, hi grade type |
| Breast CA. Tx of LCIS vs. DCIS | LCIS. DCIS tx Observation. Surgical excision (some pt opt for. (BCT w RTX +/- Tamo B/l MMectomy due to Or mastectomy alone) Being multifocal, b/l). X -tamoxifen in ER + dec. -tamoxifen above Inv CA 56%. X |
| BREAST CA. SVV benefit and DCIS tx w RTX or tamoxifen | No svv benefit w neither |
| BR CA. Is adjutant tx given in carcinoma in situ | No |
| BR a. How is invasive BR CA divided | Localized. Mtt (stage 0-3). (stage4) |
| BR CA. What are the progn factor in Localized invasive breast cancer( 4) | 1. Presence of LN mtt (most important) 2. Size of tm 3. HER2/neu (bad) 4. E/P (good) |
| BREAST Ca. Tx of invasive BR CA is in two parts | Local control. Systemic -BCT + RT. -Adjutant tx ( dec recurrence Or mastectomy. At distance sites) |
| INVASIVE BC. Local control in tx options expanded BB2. | 1. Breast conserving tx (lumpectomy)= excision of 1ry tm ( < 5 cm) + ipsilat Rtx --> 5 yrs of endocrine tx if ER/EP + ( premeno- use tamoxifen, postmeno use AI) 2. Mastectomy. Usu no Rtx, (except in large tm > 5 cm, w/ 4 or more positive axillary LN, close surgical margins, or dermal invasion) * svv is iqual * most cases invasive BC use adjuvant chemotx |
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