| Term | Definition |
|---|
| Mitochondria evidence of bacterial origin 1 | Circular DNA |
| Mitochondria evidence of bacterial origin 2 | Reproduce by binary fission |
| Mitochondria evidence of bacterial origin 3 | Double membrane |
| # of mitochondrial genes encoding proteins | 1500 |
| # of mitochondria genes present in mtNDA | 37 |
| Mitochondria in average cell | 300 |
| Decreased mitochondrial activity caused by drugs | Statins, Aspirin, Valproic acid, cyanide |
| Oxidant | Molecule accepts and electron |
| Free radical | molecule with unpaired electron |
| ROS | Reactive oxygen species |
| Superoxide | O2- |
| DNA/RNA Radical damage | Genetic mutations |
| Protein radical damage | denaturating, unfolding, misfolding |
| Carb radical damage | glycation, non enzymatic binding to proteins |
| Lipid radical damage | peroxidation |
| Telomere aging | ROS shortens telomeres, coding DNA gets exposed and lost |
| Antioxidant enzymes | Actively decrease oxidant damage potential |
| Iron Sequestration | Chelation of iron by proteins |
| Free Radical Scavengers | Passively absorb damage - vitamin A, C, E |
| Phytochemicals | free radical scavengers(?) |
Combine with other sets
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