Chapter 6 Pharm
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Created by:
amberwilloughby22 on April 6, 2012
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28 terms
Terms | Definitions |
|---|---|
 Ocular Cholinergic Effects | Lacrimation, Miosis, Accommodation |
| Cardiac Cholinergic Effects | Decreased Heart rate, increased conduction time at the AV node |
| Vascular Cholineric Effects | Vasodilation (M3 receptors), sildenafil (Viagra) potentiates the vasodilatory effects of ACh by inhibiting the breakdown of cGMP |
| Pulmonary Cholinergic Effects | broncoconstriction, increased mucous production } Cholinergic Toxicity |
| GI Cholinergic Effects | Increased HCl production, contraction (parastolsis), and saliva production |
| GU Cholinergic Effects | Increased bladder tone and decreased internal bladder sphincter tone |
| Ocular Cholinergic Inhibition | Mydriasis, Loss of ability to accommodate for near vision |
| Cardiac Cholinergic Inhibition | increased HR, decreased AV conduction time |
| Pulmonary Cholinergic Inhibition | broncodilation and inhibition of secretions |
| GI Cholinergic Inhibtion | decreased lower esophageal sphincter, inhibit gastric acid secretion, decreased motility (use this if have diarrhea), decreased saliva production |
| GU Cholinergic Inhibition | Relaxation of detrusor muscle of urinary bladder |
| Norepinephrine | no effect at autonomic ganglia |
| Norepinephrine | no effect at nicotinic and muscarinic receptors |
| norepinephrine | no effect at dopamine receptors |
| Norepinephrine | stimulatory at all sympathetic receptors |
| Norepinephrine | removed primarily by neuronal reuptake |
| norepinephrine | also inactivated by COMT and MAO (both are enzymes) |
| ganglia are all _______ | nicotinic |
| Alpha 1 Sympathetic Recpetors | vascular, on the smooth muscle of arteries and veins, cause constriction |
| Alpha 2 Sympathetic Receptors | presynaptic autoreceptors, norepinephrine can bind to this and inhibit the production of neripinephrine |
| Beta 1 Sympathetic Receptors | cardiac, make SA node fire and ventricles contract more quickly |
| Beta 2 Sympathetic Receptors | pulmonary and vascular, opens airways and blood vessels --- drop BP and Tx for asthma |
| Beta 3 Sympathetic Receptors | Adipose Tissue (help you burn fat) |
| Alpha 1 Effects | contraction of vascular smooth muscle, iris dilator muscle resulting in pupilary dilation, and bladder sphincter muscle, decreased gut motility and increased platelet aggregation |
| Alpha 2 Effects | decrease aqueous humor production, decrease insulin secretion, imidazoline receptors reduce the sympathetic outflow from CNS, central and peripheral receptors |
| Beta 1 Effects | increased HR, contractility, conduction and renin secretion from renal juxtaglomerular cells |
| Beta 2 Effects | relaxation of bronchial, uterine (stop labor) and vascular smooth muscle (lower BP), hepatic glycogenolysis, decreased gut motility |
| Beta 3 Effects | Lypolysis in adipose tissue |
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