5 Written questions
5 Matching questions
- The connective tissue layer
- 1. They provide the framework for tumor growth
2. They provide signal proteins that stimulate cell growth and division,
3. They secrete proteases that further remodel the extracellular matrix
- The basal layer and stain dark purple
- Cells isolated from breast and colon cancer have accumulated ~1 amino acid change in 100 different proteins, but alterations in only 20 of these genes are likely needed for tumor progression
- a The layer underneath the basal layer of the cervix is what?
- b Actively dividing epithelial cells in the cervix are confined to what layer? They stain what color?
- c Tumorigenesis requires the assistance of other cell types. What are the functions of these cells?
- d What evidence supports the fact that it is not simply the accumulation of large number of mutations that gives rise to a tumor?
Which picture shows normal epithelium (of the cervix)?
5 Multiple choice questions
- What is a malignant cancer arising from epithelial cells?
- In fibroblast cells, cellular division stops after how many divisions?
- Cancer is clonal in nature but cancer does not arise from what?
- The invasiveness expressed in metastasis requires what?
- What is an invasive tumor; cancer?
5 True/False questions
1) Cells that reproduce in defiance of normal restraints
2) Cells that invade areas normally reserved for other cells → What is the defining property of metastasis?
Cell proliferation which leads to an increased probability of tumor progression by increasing the number of cells containing the initial mutagenic event → Tumor promoters induce a inflammatory response which results in what? Increasing the probability of what?
Chemical carcinogens and radiation → What gives rise to malignant cancer?
Micrometasis → What process makes a 'tumor' a 'cancer'?
Telomerase → At the time of detection, how long have cancer cells been growing?