5 Written Questions
5 Matching Questions
- Genetic and epigenetic changes
- Blood supply
- 1. Self-sufficient for growth and proliferation
2. Insensitive to anti-proliferative extracellular signals
3. Less prone to undergo apoptosis
4. Defective in control mechanisms to stop cell division
5. They induce help from the surrounding stromal cells
6. They induce angiogenesis
7. They can escape from their home tissue and can
proliferate in an alternate site
8. They are genetically unstable
9. They produce telomerase, or acquire other ways to stabilize their telomeres
- a What are properties that contribute to cancerous growth?
- b Development of cancerous cells can take many, many years and is a process driven by what kind of changes?
- c At the time of detection, how long have cancer cells been growing?
- d Pro-angiogenic factors act to attract what to the area?
- e What is the process of forming new blood vessels?
5 Multiple Choice Questions
- Cytochrome P450 converts toxins into harmless and easily secreted compounds. However, modification by P450 may generate a product that is extremely what?
- The inactivated gene products normally protect against tumor progression, therefore their loss promotes what?
- The transport of tumor cells through the tissues and into the circulatory system is a difficult step as the cell must cross what two layers?
- Replicative cell senescence is controlled by what, an enzyme required for the maintenance of the repeative ends of
- Cancer cells have a high rate of genetic changes and are therefore what?
5 True/False Questions
Increased cell proliferation increasing the probability of tumor progression. → Most cancers are identified when?
Age → Is it only the accumulation of a large number of mutations that gives rise to a tumor?
Generations and involve a large element of chance → A cell accumulates a mutation that acts to enhance its own proliferation or decrease its death. These changes occur over what?
Benign tumor → What is formed by a cell mass that was able to escape its original location and enter the blood or lymphatic vessels to form secondary tumors?
Cancerous cells by activating cell proliferation through the use of a "tumor promoter" → Cells that have been primed by treatment with a known chemical carcinogen (i.e. a tumor initiator) can be induced to form what? By activating cell proliferation through the use of what?