pharm t3 ch 71

Created by s309377 

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8 terms

Hypothalamus leads to corticotropin releasing hormone leads to anterior pituitary leads to adrenocorticotropic hormone leads to adrenal cortex leads to cortisol

.

corticosteroids metabolically are catobolic in nature and they will do what to blood sugar? what will they do to protein synthesis? They stimulate what?

they will elevate blood sugar and suppress protein synthesis. Stimulate lipolysis and cause fat redistribution.

corticosteroids adrenal glands produce large amounts of

stress?

explain water and electrolytes r/t corticosteroid

insufficient amounts cortisol/will die without. causes na/h20 retention and k wasting.

corticosteroids matures what system in neonates

the respiratory system

what are therapeutic uses of corticosteroids?

rheumatoid arthritis, lupus, bowels, allergies,ASTHMA, dermatologic, cancers, preterm labor

adverse effects r/t corticosteroids

adrenal insufficiency, glucose intolerance- elevates blood sugar and unmasks diabetes, psychosis involving hallucinations/moodiness/insomnia, peptic ulcer disease especially in combination with nsaids

what is important involving adrena suppresion r/t stress and glucocorticoid withdrawal-

cannot stop abrutly must taper off****

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