pharm t3 ch 71
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8 terms
Terms | Definitions |
|---|---|
Hypothalamus leads to corticotropin releasing hormone leads to anterior pituitary leads to adrenocorticotropic hormone leads to adrenal cortex leads to cortisol | . |
corticosteroids metabolically are catobolic in nature and they will do what to blood sugar? what will they do to protein synthesis? They stimulate what? | they will elevate blood sugar and suppress protein synthesis. Stimulate lipolysis and cause fat redistribution. |
corticosteroids adrenal glands produce large amounts of | stress? |
explain water and electrolytes r/t corticosteroid | insufficient amounts cortisol/will die without. causes na/h20 retention and k wasting. |
corticosteroids matures what system in neonates | the respiratory system |
what are therapeutic uses of corticosteroids? | rheumatoid arthritis, lupus, bowels, allergies,ASTHMA, dermatologic, cancers, preterm labor |
adverse effects r/t corticosteroids | adrenal insufficiency, glucose intolerance- elevates blood sugar and unmasks diabetes, psychosis involving hallucinations/moodiness/insomnia, peptic ulcer disease especially in combination with nsaids |
what is important involving adrena suppresion r/t stress and glucocorticoid withdrawal- | cannot stop abrutly must taper off**** |
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