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Adenovirus

respiratory infection, conjunctivitis

Parvovirus

B19 (fifth disease/erythema infectiosum, fetal death, aplastic crisis)

Reoviridae

Rotavirus (infantile gastroenteritis)

Filoviridae

Ebola virus (ebola), marburg virus

Paramyxoviridae

Parainfluenza virus; Mumps virus; Respiratory syncytial virus; Morbillivirus (mumps); Pneumovirus; Metapneumovirus

Orthomyxoviridae

Influenza A, B and C

Picornaviridae

Enterovirus (Poliovirus, coxsackie A and B, echovirus, enterovirus), Rhinovirus, Heparnavirus

Caliciviridae

Norwalk (gastroenteritis)

Flaviviridae

Yellow fever virus (yellow fever); Hepatitis C (hepatitis)

Togaviridae

Eastern Equine encephalitis virus (encephalitis); Rubella virus (rubella)

HSV-1

Cold sores, encephalitis

HSV-2

Herpes genitalis, meningitis

reactivation of varicella-zoster virus

Herpes zoster, herpes zoster ophthalmicus

Epstein-Barr virus

Infectious mononucleosis

Cytomegalovirus

congenital (birth defects, low birth weights, microcephaly), STD, blood/organ transplants, immunosuppressed patients

Human herpesvirus 6 and 7

Exanthem subitum (Roseola) in children and in AIDS patients

Human herpesvirus 8

Kaposi-Sarcoma-Associated Herpesvirus

Poxvirus

Molluscum contagiosum, smallpox

Picornavirus

Poliomyelitis (polio)

Rhinovirus

common cold

Coxsackievirus A16

Hand-foot-and-mouth disease

Coxsackievirus A

herpangina

Coxsackievirus B

Myocardial or pericardial infection (high mortality)

Coxsackievirus or echovirus

viral meningitis

Norovirus

food-borne gastroenteritis; cruise ships

Parainfluenza virus

croup

Coronavirus

SARS, common cold

Respiratory syncytial virus

bronchiolitis and pneumonia in infants and children

Mumps virus

•Epidemic parotitis; painful swelling of parotid
salivary glands
•Humans = only reservoir.
•Long-term immunity.
•Live attenuated vaccine MMR

Morbillivirus

Mumps, measles

Paramyxoviruses

distemper virus in dogs and seals; morbillivirus in dolphins and porpoises; Newcastle disease virus (birds); Rinderpest virus (cows)

Henipavirus

zoonotic, reservoir is fruit bats

Henipavirus (paramyxoviridae family)

Hendra virus (HeV) and Nipah virus (NiV)- biosafety level 4

Pneumovirus

Respiratory syncitial virus (RSV; bronchiolitis and pneumonia) and Metapneumovirus (colds, bronchiolitis, and pneumonia)

Metapneumovirus

colds, bronchiolitis, and pneumonia

Influenza

respiratory symptoms and the classic
flulike symptoms of fever, malaise, headache and
myalgias

Rhabdovirus

rabies

Ebola virus

widespread tissue necrosis; endothelial damage leads to vascular injury and bleeding; hemorrhage leads to hypovolemic shock; severe hemorrhagic fever; fatal in 90% of infections

Rotavirus

Human infantile gastroenteritis- endemic, severe
diarrheal illness

Flavivirus

Yellow fever, West Nile encephalitis

Arbovirus

Flavivirus and togavirus

Flavivirus

Hepatitis C virus

Togavirus

Rubivirus (cause of rubella)

Yellow fever

high fever, yellowing of skin and eyes, coffee-ground emesis, severe liver damage, severe renal tubule damage; mosquito vector; "re-emerging disease"

Togavirus

Western and Eastern equine encephalitis (WEE and EEE)

Western and Eastern equine encephalitis (WEE and EEE)

low-grade, flulike symptoms; can progress to encephalitis; resolves spontaneously; mosquito vector

Flavivirus

West Nile virus

West Nile virus

Headache, Fever, Rash, Fatigue, Weakness; rare cause of encephalitis and paralysis; mosquito vector

Bunyavirus

California encephalitis; Rift Valley fever; Korean hemorrhagic fever; American _____ = hantavirus, A.K.A. Sin Nombre - emerging disease

Arenavirus

Lassa fever, Argentine hemorrhagic fever, Bolivian
hemorrhagic fever, and Lymphocytic choriomeningitis

Hepatitis A Virus

causes jaundice in high percentage of cases; oral-fecal route; spread in daycare; no chronic infection

Hepatitis B Virus

the only DNA virus; transmitted via blood, STD; causes chronic persistent and active hepatitis; leads to hepatocellular carcinoma and cirrhosis of liver

Hepatitis C Virus

transmitted via blood; no protective antibody response identified; leads to chronic persistent hepatitis, chronic active hepatitis, cirrhosis, and hepatocellular carcinoma but less than HBV

Hepatitis D Virus

similarity to viroids in plants; coinfection and superinfection with HBV; transmitted sexually and through blood

Hepatitis E Virus

calicivirus-like; transmitted through fecally contaminated drinking water

Prions

Causes transmissible spongiform
encephalopathies (TSEs) in humans and
animals and neurodegenerative diseases with long
incubation periods

Prions

Kuru, Creutzfeldt-Jakob Disease (CJD), and Variant CJD (vCJD)

Creutzfeldt-Jakob Disease (CJD)

alteration in the structure of normal PrP protein found in the brain that results in nerve cell death, spongiform damage, and severe loss of brain function

Papillomavirus

warts

Polyomavirus

BK and JC viruses; associated with renal disease (BK) and progressive multifocal leukoencephalopathy, aka PML (JC) in immunosuppressed people

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