How genes work ch. 15

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katiehedquist  on April 16, 2012

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How genes work ch. 15

gene expression
the process of converting archived information into molecules that actually do things in the cell.
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Terms

Definitions

gene expression the process of converting archived information into molecules that actually do things in the cell.
the one-gene, one-enzyme hypothesis ach gene is made of only one enzyme
knock-out mutants alleles that do not function at all
mRNA messenger RNA are short-lived molecules that carry info from DNA to the site of protein synthesis
RNA polymerase polymerizes ribonucleotides into strands of RNA.
central dogma summarizes the flow of info in cells. an accepted version of the way things are/happen.
Transcription the process of copying hereditary information in DNA to RNA.
Translation the process of using the information in nucleic acids to synthesize proteins.
genetic code the rules that specify the relationship between a sequence of nucleotides in DNA or RNA and the sequence of amnio acids in a protein.
triplet code a three-base code
codon the group of three bases that specifies a particular amino acid
start codon signals that protein synthesis should begin at that point on the mRNA molecule.
stop codon termination codons that signal the protein is complete and end the translation process.
mutation any permanent change in an organism's DNA
point mutation a single base change
missense mutations a point mutation that causes a change in the amino acid sequence of a protein. Change in primary polypeptide structure. ch
silent mutations a point mutation that does not change the amino acid sequence of the gene product. A change in the genotype but not the phenotype
nonsense mutation change in nucleotide that results in early stop codon
beneficial increase the fitness of the organism
neutral mutation has no affect on fitness
deleterious lower fitness
frameshift addition or deletion of a nucleotide
polyploidy a change in the number of each type of chromosome present
aneuploidy the addition or deletion of a chromosome
inversion segments become flipped and rejoin
translocation become attached to a different chromosome
karyotype the complete set of chromosomes in a cell

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