1.
A good choice of medication therapy for patients with HIV and HBV co-infections is what?: lamivudine
2.
Abacavir is a nucleside reverse transcriptase inhibitor and is an ingredient in the triple antiretroviral therapy that combines abacavir with AZT and _____.: lamivudine
3.
AIDs "cocktails" are made up of ___ or more medications.: 3 or more
4.
All of the following are classes of antiretrovirals except _____.
a. nucleoside reverse transcriptase inhibitors (NRTIs)
b. non-nucleoside reverse transcriptase inhibitors (NRTIs)
c. acyclic phosphonate nucleotide analog
d. fusion inhibitors: c. acyclic phosphonate nucleotide analog
5.
Efavirenz is teratogenic are classified in what pregnancy category?: category D
6.
Effective treatment of viral infections is dependent on what factors?: host, virus, drug
7.
Human immunodeficiency virus (HIV) is the virus that causes acquired immune deficiency syndrome (AIDS). The virus attacks what and weakens the immune system.: CD4T lymphocytes
8.
T/F: Antiretroviral therapy is a life-long commitment and requires strict adherence to treatment regimens.: true
9.
T/F: Antiviral medications are effective against all viruses.: false
10.
T/F: Antivirals are not virucidal; they are virustatic.: true
11.
T/F: Interferons are classified as antiviral agents.: false
12.
T/F: There are eight steps in the HIV life cycle.: false; there is nine steps
13.
The FDA requires the manufacturer of ____ to provide a black box warning in the package labeling regarding reports of fatal and non-fatal intracranial hemorrhage.: tipranavir
14.
The importance of treating herpes simplex virus is the timing of initiation of drug therapy. Severity of the infection and symptoms are reduced only when antiviral therapy is initiated within the first ____ hours of exposure to the virus or onset of symptoms.: 24-48 hours
15.
The mechanism of action of what drug used to treat RSV is not completely understood, but it is believed that the drug increases the mutation rate of the virus leading to a growing number of viruses unable to replicate?: ribavirin
16.
The only drug in the fusion inhibitor class is _____.: enfuvirtide
17.
What class is atazanavir?: protease inhibitor
18.
What class is cidofovir?: acyclic phosphonate nucleotide analog
19.
What class is didanosine?: nucleotide reverse transcriptase inhibitors
20.
What class is interferon?: PEG-intron
21.
What class is nevirapine?: non-nucleotide reverse transcriptase inhibitors
22.
What is associated with fatal liver toxicity and the FDA has required changes in the package labeling to warn of this adverse effect?: nevirapine
23.
Which drug is not FDA approved, but is used for the treatment of herpes infections?
a. valacyclovir
b. cidofovir
c. acyclovir
d. foscarnet: b. cidofovir
24.
Which of the following drugs is used to treat influenza A?
a. amantadine
b. rifampin
c. rimantidine
d. amantadine and rimantidine: d. amantadine and rimantidine
