Chapter 13

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45 terms · Viruses, Viroids, and Prions Jen Mc

In which of the following ways do viruses differ from bacteria?

Viruses are not composed of cells

Which of the following statements provides the most significant support for the idea that viruses are nonliving chemicals?

They cannot reproduce themselves

Which of the following statements about spikes is false?

They are used for penetration

Which of the following is NOT used as a criterion to classify viruses?

Biochemical tests

Which of the following is NOT a method of culturing viruses

In culture media

Bacteriophages and animal viruses do NOT differ significantly in which one of the following steps?

Biosynthesis

The definition of lysogeny is

Phage DNA is incorporated into host cell DNA

A viroid is

A nonenveloped, infectious piece of RNA

In figure 13.1, which structure is a complex virus

B
looks like a rocket with legs

In figure 13.1, the structures illustrated are composed of

Capsomeres

A clear area against a confluent "lawn" of bacteria is called a

Plaque

Continuous cell lines differ from primary cell lines in that

Continuous cell lines can be maintained through an indefinite number of generations

Which of the following is necessary for replication of a prion?

pSc

A persistent infection is an infection in which

The disease process occurs gradually over a long period

Which of the following statements is false?
A. A prophage is phage DNA inserted into a bacterial chromosome
B. A prophage can pop out of the chromosome
C. Prophage genes are represented by a repressor protein coded for by the prophage
D. A prophage may result in new properties of the host cell
E. The prophage makes the host cell immune to infection by other phages

The prophage makes the host cell immune to infection by other phages

Lysogeny can result in all of the following EXCEPT

Immunity to reinfection by any phage

Which of the following would be the first step in biosynthesis of a virus with a - strand of RNA

Synthesis of double-stranded RNA from an RNA template

An infectious protein is a

Prion

An envelope is acquired during which of the following steps?

Release

Which of the following contributes to the difficulty in establishing the etiology of cancer?
A. Most viral particles can infect cells without inducing cancer
B. Cancer may not develop until long after infection
C. Cancers do not seem to be contagious
D. Viruses are difficult to observe
E. All of the above

All of the above

An example of a latent viral infection is

Cold sores

The most common route of accidental AIDS transmission to health care workers is

Needlestick

Assume you have isolated an unknown virus. It is a single-stranded RNA, enveloped virus. To which group does it most likely belong?

Togavirus

To which group does a small, nonenveloped single-stranded RNA virus most likely belong?

Picornavirus

The most conclusive evidence that viruses can cause cancers is provided by

Cancer following injection of cell-free filtrates

Bacteriophages derive all of the following from the host cell EXCEPT

Lysozyme

Generalized transduction differs from specialized transduction in that generalized transduction

Transfers specific DNA

Generally, in a DNA-containing virus infection, the host animal cell supplies all of the following EXCEPT

DNA polymerase

Put the following in the correct order for DNA-virus replication
1-Maturation
2-DNA synthesis
3-Transcription
4-Translation

2,3,4,1
DNA synthesis, Transcription, Translation, Maturation

A viral species is a group of viruses that

Have the same genetic information and ecological niche

Viruses that have reverse transcriptase are in the

Hepadnaviridae and Retroviridae
(Hepatitis and HIV)

DNA made from an RNA template will be incorporated into the virus capsid of

Hepadnaviridae

Which of the following statements about viruses is false?
A. Viruses contain DNA or RNA but never both
B. Viruses contain a protein coat
C. Viruses use the anabolic machinery of the cell
D. Viruses use their own catabolic enzymes
E. Viruses have genes

Viruses use their own catabolic enzymes

Approximately how many virus particles could fit along a 1 millimeter line?

20,000

Some viruses, such as human herpesvirus 1, infect a cell without causeing symptoms; these are called

Latent viruses

Assume a patient had chickenpox (human (herpesvirus 3) as a child. Which line on the graph in Figure 13.2 would show the number of viruses present in this person as a 60 year old with shingles (human herpesvirus 3)?

E
Latent

Assume a patient has influenza. During which time (on the graph in Figure 13.2) would the patient show the symptoms of the illness?

C
Acute

The following steps occur during multiplication of herpesviruses. What is the third step?

Uncoating

The following steps occur during multiplication of retroviruses. What it the fourth step?

Synthesis of double-stranded DNA

Nontoxic strains of Vibrio cholerae can become toxic when they are in the human intestine with toxic strains of bacteria. This suggests that the toxin genes are acquired by

Transduction

Which of the following steps does NOT occur during multiplication of a picornavirus (single stranded RNA)?

Synthesis of DNA

Which of the following is most likely a product of an early gene?

DNA polymerase

Most RNA viruses carry which of the following enzymes?

RNA-dependent RNA polymerase

The following steps occur during biosynthesis of a + strand RNA virus. What is the third step?

Synthesis of a - strand RNA

What contributes to antigenic shift in influenza viruses?

Segmented genome

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