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To which lymph nodes does the following region drain? -Rectum Internal iliac nodes To which lymph nodes does the following region drain? -External anus Superficial inguinal nodes To which lymph nodes does the following region drain? -Testes Superficial and deep plexuses → para-aortic nodes To which lymph nodes does the following region drain? -Scrotum Superficial inguinal nodes To which lymph nodes does the following region drain? -Sigmoid colon colic → inferior mesentaric Where can B cells and T cells be found in the lymph nodes? B cells: follicles of the cortex T cells: Paracortex 1. Which MHC are found in T helper cells? 2. Which MHC are found in cytotoxic T cells? 1. T helper cells= MHC II 2. cytotoxic T cells = MHC I What characteristic findings would you seen on electron microscopy of a dendritic cell with Langerhans cell histiocytosis? Birbeck granules ("tennis rackets") What molecules are expressed on the surface of antigen presenting cells? MHC Class II Fc receptors What are the 3 cell types that are known for presenting antigen to T cells? Dendritic cells B cells Macrophages What hematologic changes would you expect to see in a patient without a functional spleen? -Howell-Jolly bodies -target cells -thrombocytosis What substances are utilized by natural killer cells to induce apoptosis in other cells? granzymes and perforin