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What are the most common lab animals?

rats & mice

Rats & mice make up what % of lab animals?

95

Refinement

methods that incorporate modification of a procedure to lessen animal pain & distress & enhance animals well-being

Reduction

reducing # of animals used for research

BSL 3

exotic agents with potential for aerosol transmission, decontaminaion of wastes & clothes, full body pressure suit, double doors, eye wash readily available

Why are shrews used in lab medicine?

they can V+

Who is Dolly?

the first mammal to be cloned from an adult cell

When was Dolly born?

1996

BSL 4

dangerous agents, high risk of diz, aerosol transmitted lab infx, shower on exit, all decontaminated, seperate building, isolated zone

BSL 2

associated with human dz; per cutaneous injury, mm exposure, ingestion; coats, gloves, face protection PRN

What did Jonas Salk develop?

the polio vx

Where was the polio vx developed?

Pitt

Who developed the Germ Theory?

Louis Pasteur

What's the germ theory?

microorganisms cause dz

BSL 1

not known to cause dz, standard microbiological practices, no safety equipment required

Animals not covered in the animal welfare act

lab mice, rats & birds; agriultural animals used for food/fiber; fish, reptiles, amphibians, invertebrates

Replacement

non animal alternatives or using less advanced animals

AALAS AKA

American Association for Lab Animal Science

ALAT AKA

Assistant Lab Animal Tech

LAT AKA

Lab Animal Tech

LATG AKA

Lab Animal Technologist

How often does IACUC inspect?

q 6 mos

How long is IACUC protocol good for?

3 yrs

Is the USDA federally mandated?

yes

How often does USDA inspect?

once a year

Is USDA announced or unannounced?

unannounced

IACUC AKA

Institutional Animal Care & Use Committee

Is IACUC federally mandated?

yes

Who is in IACUC?

6 people - 1 must be a vet, 1 must be unbiased

Is IACUC announced or unannounced?

announced

Who was the first to perform experiments on living animals?

Aristotle

Is AALAC federally mandated?

no

How often does AALAC inspect?

q 3 yrs

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