Cards II Pharm

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Created by:

dialsquare  on April 24, 2012

Subjects:

first aid, pharm

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Cards II Pharm

drugs that increase cGMP
hydralazine, nitroprusside, nitroglycerin
1/19
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drugs that increase cGMP hydralazine, nitroprusside, nitroglycerin
aphrodisiac and erection enhancer nitroglycerin, isosorbide dinitrate
K+ channel opener
-hyperpolarizes and relaxes vascular smooth muscle-
diazoxide
reduces insulin release
-can cause hyperglycemia-
diazoxide
D1 receptor agonist
-relaxes renal vascular smooth muscle-
fenoldopam
can cause cyanide toxicity nitroprusside
release of nitric oxide nitroprusside, nitrates
decreases preload nitroglycerin, isosorbide dinitrate
blocks voltage-dependent L-type calcium channels
of cardiac and smooth muscle
calcium channel blockers
reduces muscle contractility calcium channel blockers
what type of calcium channels do calcium channel blockers block? L-type (voltage-dependent)
reduces afterload hydralazine
effect of calcium channel blockers on vascular smooth muscle
by drug
nifedipine > diltiazem > verapamil
effect of calcium channel blockers on heart
by drug
verapamil > diltiazem > nifedipine
calcium channel blocker not used to tx arrhythmias nifedipine
causes Monday Disease nitrates
freq given with beta blocker to prevent reflex tachycardia hydralazine
causes reflex tachycardia hydralazine, nitroglycerin, isosorbide dinitrate
causes lupus-like syndrome hydralazine

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dialsquare