Pneumonia

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Created by:

neilparikh  on April 24, 2012

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Pneumonia

mucociliary elevator
The ciliated mucus lining of the trachea, bronchi, and bronchioles that sweeps foreign particles up and away from the lungs.
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mucociliary elevator The ciliated mucus lining of the trachea, bronchi, and bronchioles that sweeps foreign particles up and away from the lungs.
alveolar macrophage waiting in lungs to ingest and kill organisms
Routes of Spread of bacteria 1) asipration of oropharyngeal secretions (Streptococcus Pneumoniae)
2) inhalation of droplets (TB)
3) hematogenous (Staph Aureus)
sneezing or coughing release refined food particles--evaporate quickly but last about 3 feet from the person who was coughing
which bacteria often cause abscesses in the lung? Staph Aureus, gram - rods;
-see an air-fluid level
causes of Community associated pneumonia? 1) s. pneumoniae (45%)
2) viral - 12.5%
Treatments CAP: if no comorbidities, treat outpatient; usually is: S. pneumoniae or H. influenzae or viral;

all treated with macrolides (eg azithromycin) or Respiratory Fq (levofloxacin/doxycycline)
CAP WITH comorbidities treat at outpatient

could be S. pneumoniae, H. influenzae PLUS S. aureus, anaerobes, coliforms

Treat with: Respiratory Fq or Amox+clav + macrolide
Hospitalized Resp FQ alone or macrolide (azithromycin) + 3rd gen cephalosporin (eg ceftriaxone)
Hospitalized in ICU could be...S. pneumo, Legionella, Coliforms, Pseudomonas (ventilated)

Treat with WIDE SPECTRUM:

Imipenem, meropenem, or Pip/tazo + aminoglycoside (streptomycin, gentamycin, etc.)
prevention Give @ risk population (>65, or immunocomrpomised)--

1) pneumovax - 23 strain vaccine
2) protein form for children

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