5 Written Questions

1. last line against MRSA
2. alters membrane permeability; kills flatworms
3. Zanamivir : influenza
4. 1) enzymatic destruction of a drug
   2) prevention of penetration of drug
   3) alteration drug's target site
   4) rapid ejection of drug
5. enfuvirtide : HIV

5 Matching Questions

1. synergism
2. isoniazid & ethambutol
3. Antifungals
4. penicillinase
5. streptomycin

1. a effects of drugs compounded together
2. b breaks beta lactam ring
3. c drugs targeting membrane sterols
4. d changes shape of 30s portion, causing mrna to be encoded incorrectly.
5. e antimycobacterials

5 Multiple Choice Questions

1. UTI & inhibit DNA replication
   1. Quinolone & fluoroquinolones
   2. Cephalosporins
   3. sulfonamides
   4. isoniazid & ethambutol
2. binds to 50s & inhibits formation of peptide bonds
   1. Carbapenems
   2. chloramphenicol
   3. sulfonamides
   4. niclosamide
3. cell wall synthesis
   1. Penicillin G
   2. Penicillin V
   3. penicillinase
   4. Penicillin
4. inhibit folic acid
   1. rifamycin
   2. sulfonamides
   3. niclosamide
   4. siRNA
5. HIV
   1. antisense agents
   2. protease inhibitor
   3. integrase inhibitor
   4. fusion inhibitor

5 True/False Questions

1. polymyxin b → anti TB & inhibit RNA synthesis

   True        False

2. broth dilution test → alters membrane permeability; kills flatworms

   True        False

3. tetracycline → anti TB & inhibit RNA synthesis

   True        False

4. Carbapenems → penicilinase resistant & effective against gram -

   True        False

5. siRNA → complementary RNA that binds mRNA to inhibit translation

   True        False