Genetics Lecture Online FInal Exam

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IRSC  on April 29, 2012

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Genetics Lecture Online FInal Exam

Antisense RNA
Blocks translation by binding mRNA
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Antisense RNA Blocks translation by binding mRNA
Nucleotides Sugar, Base, Phosphate
Cosmid Virus
Ti Plasmid Plants
BAC Up to 1000kb
Northern Blotting RNA transferred from a gel to a solid support
Southern Blotting DNA from gel to medium
Western Blotting ...transfer of protein from a gel to a membrane.
probe used is usually an antibody
When homologous chromosomes and sister chromatids separate in meiosis Meiosis I
RB protein Prevents cell from passing G1-S transition
chromosome structure Centromere.
Pair of telomeres.
Ori
Centromere Attachment point for spindle microtubules
Telomeres Tips of a linear chromosome.
protect and stabilize chrom ends.
Separation of sister chromatids Anaphase II
Separation of homolgous chromatids Anaphase I
Nucleotides consist of Sugar
Phosphage
Base
Robert Hooke Discovered cell
Grew Plants reproduce sexually
Brown Described cell nucleus
Sheldon and Schwann Cell theory
Flemming Division of chromosomes in mitosis
Weismann Germ plant theory
Sulton Genes on chromosome
Meiosis II Separation of sister chromatids
Number of Telomeres 2 per DNA molecule
Kolreuter Crosses and pollinations
Manifestation or appearance of a characteristic Phenotype
Henking Discovered X body
McClung Recognized X body in grasshoppers was a chromosome
Alternative forms of a gene Allele
Sigma factor binds Polymerase to the promoter
Discontinuous characteristics Few easily distinguished phenotypes
Causes of Aneuploidy Deletion of centromere.
Robertsonian translocation
Nondisjunction
Effects of Aneuploidy in humans Turner syndrome (XO)
Klinefelter syndrome (XXY)
When the complementary sequences are contiguous, the hairpin Has a stem but no loop
Topoisomerase function Adding or removing rotations from DNA by nicking the strand unwinding and then rejoining
Know what the Ras pathway does Growth and stimulating factors to stimulate cell cycle
Polypeptide Amino acids in proteins joined together by peptide bonds
Sense codon Code for amino acid
Isoaccepting tRNA Different tRNAs that bind same amino acid but have different anticodons
Aminoacyl-tRNA synthetase Attaches a specific amino acid to a tRNA
RecA protein Single strand to invade DNA helix and displace 1 strand
Transition A replaces G
Transversion A replaces T

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