What are the maCerebrovascular diseases are:
CNS diseases caused by pathology of blood vessels
Major categories of CVD are:
Stroke-refers to the above 3 categories. 2 types of stokes are:
➢ Ischemic stroke
➢ Hemorrhagic stroke
NOTE: the more common situation that you will encounter is:
Thrombosis or embolism causing an ischemic stroke.
Survival of tissue at risk depends on:
➢ Collateral circulation
➢ Duration of ischemia
➢ Magnitude and rapidity of decreased flow
TIA(transient ischemic attack) decreases blood flow for longer than:
SEVERAL SECONDS and then blood flow is quickly restored. Signs and symptoms last for less than 24hrs.
Infarction is the cessation of blood flow for more than a :
FEW MINUTES (4-10min)
Ischemic penumbra states that:
The tissure surrounding the core of infaction maybe dysfunctional but reversible with early treatment.
Saving ischemic penumbra is the goal of:
every therapy....cnt save it once its infarcted bc its dead then
The most important risk factor for a stroke is a:
Amaurosis fugax is a :
Transient monocular blindness due to embolism of central retinal artery of one eye...this is a specific symptom of a TIA.
What are the 3 vascular malformations?
➢ Arteriovenous Malformations-MOST COMMON
➢ Cavernous angioma
Which vascular malformation is the MC congenital vascular malformation with the greatest clinical significance?
Arteriovenous Malformations (AVM)
S/S of Arteriovenous Malformations resemble:
S/S of a brain tumor
Does BERRY cerebral aneurysm have anything to do w/HTN?
What is the main problem with Charcot Bouchard Aneurysms?
Longstanding HTN.....HTN causes injury to arterial wall deposition of lipid and hyaline material called lipohylinosis
What arteries are often involved in Charcot Bouchard Aneurysms?
Lenticulostriate arteries and middle cerebral artery,
Does it effect the corpus striatum?
YES, corpus striatum=motor fibers→ passes to OPPOSITE side of body and may cause a CONTRALATERAL HEMIPLEGIA