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chronic, non-healing ulcer of foot; what kind of env?

necrosis, low blood supply; facilitates growth of anaerobes

ciprofloxacin

first-generation fluoroquinolone

mechanism of fluoroquinolones

DNA topoII inhibitor of bacteria; i.e. DNA gyrase

ceftriaxone

third-gen cephalosporin; gram -s, enterics

enterics

H. flu, Klebsiella PNA, Neisseria, Serratia

vancomycin acts on

cell wall synthesis e.g. gram + orgs like Staph, including MRSA, C. diff

azithromycin

macrolide that binds 50S e.g. intracell orgs like Chlamydia, mycoplasma

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