5 Written questions
5 Matching questions
- cytotoxic antibiotics
- alkylating agents
- Potassium Channel Blockers
- bile acid resins
- Beta Blockers
- a bradycardia, hypotension, dizziness, fainting, risk for bronchospasm, diminished sex drive and impotence
- b bone marrow suppression is primary dose-limiting adverse effect. red blood cells, white blood cells, and platelets begin to decline quickly. nausea, vomiting, diarrhea. alopecia is expected
- c major dose-limiting adverse effect is bone marrow suppression. adverse effects are similar to those of the alkylating agents
- d GI disturbances. constipation, bloating, nausea, indigestion. self-medication with niacin can cause gout and liver damage from high doses. it will not lower cholesterol at low doses. take 1 hour before or 4 hours after other meds. dissolving it in water and keeping fluid intake high helps to avoid irritation of the mouth and constipation
- e bradycardia, possibly hypotension, can worsen dyrshythmias. most serious is a pneumonia-like syndrome. blurred vision, rashes, photosensitivity, nausea, vomiting, anorexia, fatigue, dizziness
5 Multiple choice questions
- ALLERGY most common. (s/s allergy: rash, fever, and anaphylaxis) diarrhea, nausea, and vomiting. Anaphylaxis is most serious.
- flulike syndrome of fever, chills, dizziness, and fatigue, headache, nausea, vomiting, diarrhea, and anorexia. depression and suicidal ideation have been reported. with prolonged therapy, immunosuppression, serious toxicity such as hepatotoxicity and neurotoxicity may be observed
- most common are intense buring sensation in the nose immediately after spraying and drying of the nasal mucosa. nasal irritation and bleeding occur in a few pts.
- severe toxicity to blood cells at high doses. anemia and leukopenia are common, headache, generalized weakness, anorexia, nausea, diarrhea, lactic acidosis.
- headache, insomnia, upper abdominal pain, decreased appetite, and cough
5 True/False questions
thrombolytics → dehydration is one of most common. electrolyte imbalances most common. hypokalemia (loss of Potassium) or hyperkalemia (high levels of potassium; occurs when taking potassium supplements with potassium-sparing diuretics)
organic nitrates → depress CNS function, drowsiness, withdrawal syndrome is extremely severe and can be fatal. overdose results in profound respiratory depression, hypotension, and shock. at high doses some can produce anesthesia
anticoagulants → BLEEDING.
antimetabolites → flulike syndrome, headache, diarrhea, dizziness, bruising, upper respiratory tract infection, and rash or pruritus. GI bleeding can occur. Excessive bleeding is a potential adverse effect
insulins → heartburn. uncommon unless given in high doses. at high doses, can cause GI discomfort and bleeding