Glycogen Metabolism
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Created by:
wookieman3 on May 2, 2012
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8 terms
Terms | Definitions |
|---|---|
 Phosphorylase Kinase | Part of the signal cascade involved in glycogen degredation. Is phosphorylated by Protein Kinase A. Activates Phosphorylase b to Phosphorylase a. |
| Phosphorylase b | Inactive form, found primarily in muscle in it's T state. |
| Phosphorylase a | Active form, found primarily in the liver in its R state. |
| Phosphorylase | Phosphorylates glycogen which releases Glucose 1-Phosphate. |
| Glucose 6-Phosphatase | Gluconeogenic enzyme involved in dephosphorylating glucose 6-phosphate to glucose. Important in regulating blood sugar. |
| Phosphoglucomutase | Converts Glucose 1-Phosphate to Glucose 6-Phosphate to proceed with glycolysis. |
| Hers Disease | Phosphorylase deficiency. Results in hepatomegaly and hypoglycemia. |
| I Von Gierke Disease | Glucose 6-Phosphatase deficiency, none in the liver. Results in hepatomegaly, hypoglycemia, failure to thrive. Treat with starch and glucose enriched diet. |
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