non radioactive pharmaceuticals used in nuclear medicine

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indication dose adverse effects antidote

Acetazolamide

Diamox
Brain perfusion imaging
1 gm in 10 mL sterile water IV over 2 min
*tingling sensation in extremities and mouth, flushing, lightheadedness, blurred vision, headache

Adenosine

Adenoscan
Cardiac stress imaging
140 ug/kg/min for 6 min, or 0.84 mg/kg
*chest discomfort, throat, jaw or neck discomfort, headache, flushing, dyspnea, ECG changes
Antidote: discontinue infusion; administer aminophylline if needed

Bethanechol

Urecholine
Gastric emptying
2.5 to 5 mg subcutaneously
*abdominal discomfort, salivation, flushing, sweating, nausea, drop in blood pressure
Antidote: atropine

Captopril

Capoten
renovascular hypertension evaluation
25-50 mg PO 1 hr before study
*orthostatic hypotension, rash, dizziness, chest pain, tachycardia, loss of taste
Antidote: saline infusion

Cholecystokinin

Kinevac
hepatobiliary imaging
0.02 ug/kg
*abdominal pain, urge to defecate, nausea, dizziness, flushing

Cimetidine

Tagamet
Meckel's diverticulum
300 mg/kg for adults
20 mg/kg IV for children
*diarrhea, headache, dizziness, confusion, bradycardia

Dipyridamole

Persantine
Cardiac stress imaging
0.57 mg/kg IV over 4 min
*chest pain, nausea, headache, dizziness, flushing, tacchycardia, shortness of breath, hypotension
Antidote: aminophylline

Dobutamine

Dobutrex
cardiac function
incremental dose rate:
over 3 min (adult)
15 ug/kg/min up to 40 ug/kg/min
*angina, tachyarrhytmia, headache, nausea, vomiting
Antidote: esmolol

Enalaprat

Vasotec
renovascular hypertension evaluation
Adult: 0.04 mg/kg (max 2.5 mg) in 10 mL saline, IV over 5 min
* orthostatic, hypotension, dizziness, chest pain, headache, vomiting, dizziness
Antidote: saline infusion

Furosemide

Lasix
renal imaging
Adult: 20-40 mg IV over 1 min
* nausea, vomiting, diarrhea, headache, dizziness, hypotension, dehydration

Glucagon

Meckel's diverticulum
Adult: 0.5 mg
Child: 5 ug/kg
*nausea, vomiting

Morphine

Astramorph/Duramorph
hepatobiliary imaging
0.04 mg/kg diluted in 10 mL saine, IV over 2 min (range 2 to 4.5 mg)
*respiratory depression, nausea, sedation, lightheadedness, dizziness, sweating
Antidote:naloxone

Pentagastrin

Peptavalon
Meckel's diverticulum
6 ug/kg subcutaneously
*abdominal discomfort, urge to defacate, nausea, flushing, headache, dizziness, tachycardia, drowsiness

Phenobarbital

Luminal
hepatobiliary imaging
5mg.kg/day orally for 5 days
*respiratory depression, nausea, vomiting, dizziness, drowsiness, headache, parodoxal excitement in children

Vitamin B12

Cyanoject/Cyomin
Schilling test
1 mg IM
*hypersensitivity reactions, transitory exanthema

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