Step 1 Signaling Pathways of Endocrine Hormones

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FSH, LH, ACTH, TSH, CRH, hCG, ADH (V₂), MSH, PTH, GHRH, calcitonin, glucagon


think vasodilators


GnRH, Oxytocin, ADH (V₁), TRH, Histamine (H₁), angiotensin II, gastrin

cytosolic steroid receptor

Vitamin D, Estrogen, Testosterone, Cortisol, Aldosterone Progesterone
think adrenal hormones + Vit. D

Nuclear steroid receptor


Intrinsic tyrosine kinase
MAP kinase pathway

Insulin, IGF-1, FGF, PDGF
think growth factors

receptor-associated tyrosine kinase
JAK/STAT pathway

Prolactin, GH, cytokines (IL-1, IL-6, IL-8)

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