What is a genome?
The complete set of genetic material in an organism.
What is non-disjunction?
Trisomy 21 is a condition caused by the failure of chromosomes to separate.
What is translocation?
When a fragment of one chromosome attaches to a non homologous chromosome.
If a person is a carrier for a sex-linked recessive disorder, what would their genotype look like?
What is the human genome project?
An attempt to sequence the human genome
What can be observed on a karyotype?
An extra chromosome
What is the failure of homologous chromosomes to separate during meiosis?
What are some genetic disorders caused by non-disjunction?
Trisomy 21, Klinefelter's, Turner's syndrome
What does an open circle represent on a pedigree?
Female does not have the disorder
What does a shaded square represent on a pedigree?
Has a disorder or condition
Why is a pedigree used?
To determine whether a trait is inherited, show how a trait is passed from one generation to the next and to determine whether an allele is dominant or recessive.
Where are the se linked alleles for colorblindness located?
On the X chromosome
What happens to gametes during non-disjunction?
Some gametes may have an extra copy of some genes.
What is deletion?
An example of chromosome damage caused by part of the chromosome to be missing.
What is duplication?
A change that occurs when part of a chromosome is repeated.
What is substitution?
Repeats part of the chromosome.
What is inversion?
Flips part of the chromosome into a different order.
What type of allele causes Huntington's disease?
Why is colorblindness more common in males than females?
The allele for color blindness is recessive and is located on the X chromosome.
If a woman is a carrier of a sex-linked trait and marries a man with the trait, what is the chance the child will have the trait?
If the person is a carrier of a trait, do they exhibit the trait?
In order to produce a male, an egg must be fertilized with a sperm carrying what type of chromosome?
What is a germ cell mutation?
Mutation that does not affect the organism but can be passed on to the offspring.
What is a somatic cell mutation?
Skin cancer resulting from over exposure to UV rays.
What is trisomy?
Three copies of the same chromosome.
What type of mutation is skin cancer.
Somatic cell mutation
If a heterozygous red-eyed fruit fly is cross with a red-eyed male, what will the offspring resemble?
Half the male offspring will be red-eyed and half will be white-eyed.
What is monosomy?
One copy of the chromosome.