Micro Bacteria

Created by krompala 

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where in bacteria are many beta lactamases?

periplasmic space

structures unique to gram+?

teichoic acid

structures unique to gram-?

endotoxin, LPS, periplasmic space

PAS stain for what bug?

Whipple's disease

India ink for what bug?

Cryptococcus

Silver stain for what bug?

fungi, legionella

Important obligate aerobes?

Pseudomonas
M. tuberculosis (explains why it reactivates in upper lobes with high O2)

Big mama anaerobes?

Clostridium
Bacteroides

Quellung + bugs?

Some Killers Have Pretty Pretty Nice Capsules
- Salmonella
- Klebsiella
- H flu
- Pseudomonas
- Strep Pneumo
- Neisseria
- Citrobacter

Urease + bugs?

P PUNCH
- Proteus
- Pseudomonas
- Ureoplasma
- Nocardia
- Cryptococcus
- H pylori

IgA protease?

SHiN: Strep pneumo, H flu, Moraxella, Neisseria (think respiratory infx, also can take up DNA from enviro aka transformation)

Toxins encoded in a lysogenic phage?

ABCDE
- ShigA-like
- Botulinum
- Cholera
- Diphtheria
- Erythrogenic toxin of S. pyogenes

3 things you don't want to take a bath in?

VOmit, ABscess, SNot
- Viridans, Optochin resistant
- Agalactiae, Bacitracin resistant
- Saprophyticus, Novobicin resistant

ADP ribosylaters?

Pertussis (inhib Gi, increased cAMP)
Cholera (stim Gs, increased cAMP)
E coli (stim Gs, increased cAMP)
C diphtheria (inactivates EF2)
Pseudomonas (inactivates EF2)

staph aureus virulence factor?

protein A

staph aureus exotoxins?

TSST: scalded skin, toxic shock syndrome

strep pyogenes virulence factor?

protein M

strep pyogenes exotoxin?

erythrogenic (scarlet fever)
TSST (toxic shock)

Clostridia toxins?

- C. tetani (tetanospasmin, blocks glycine and GABA)
- C. botulinum (blocks ACh release)
- C. perfringens (alpha toxin, lecithinas, gas gangrene)
- C. diff (Toxin A enterotoxin in gut, Toxin B cytotoxin destroying cytoskeletal structure of enterocytes leading to pseudomembranous colitis)

what bug has actin rockets to move cell to cell?

Listeria

what's a Ghon complex?

Ghon focus (lower lobes) and lobar and perihilar LN involvement (primary infection)

when do you get cavitary upper lobe TB lesions?

secondary infection

types of leprosy?

Tuberculoid (TH1, few skin nodules)
Lepromatous (TH2, diffuse, communicable, lethal)

bacteria that can cause colon cancer?

S. bovis

Diseases caused by S. pyogenes?

LINGER
Lymphangitis
Impetigo
Necrotizing fasciitis
Glomerulonephritis
Erysipelas
Rheumatic fever

chocolate agar plus factor V and X for growth?

H flu

charcoal yeast with iron and cystein?

Legionella

bug that causes Pontiac fever?

legionella

4 As of Klebsiella?

Aspiration pneumo
Abscess in lungs
Alcoholics
diAbetes

Red currant jelly sputum for what bug?

Klebsiella

common antecedant to Guillain Barre?

Campylobacter

surfer's disease?

Leptospira interrogans

stages of syphilis?

1: painless chancre
2: disseminated w/rash, condylomata
3: gumma, aortitis, neuro

causes of VDRL false positives?

VDRL
- Viruses
- Drugs
- Rheumatic fever
- Lupus, Leprosy

Clue cells under micro?

Gardnerella vaginalis (BV)

Palm and sole rash?

- Coxsackievirus A (hand foot mouth)
- Rocky Mt spotted fever
- Syphilis

repiratory droplets?

N meningitidis
H flu
TB

cause granulomas?

TB
Leprosy
Sarcoid
Syphilis
Bartonella
Listeria
Crohns

eosinophilic pneumonia?

Loeffler's (parasite)
Aspergillus
Churg strauss

causes of meningitis in neonate?

Baby BEL
Group B strep
Ecoli
Listeria

causes of osteomyelitis?

Staph aureus
Salmonella (sicle cell)
Staph epidermidis (prosthetic joint)
Pseudomonas (diabetic foot)

ELEK test for...?

Corynebacterium toxin

gas gangrene?

C perfringens

grown on cysteine-tellurite agar as dark black, slightly iridescent colonies?

C. diphtheriae

grows on Bordet-Gengou?

Bordetella pertussis

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