Osmotic diuretics have their action where?
What are two examples of osmotic diuretics
Is the action of osmotic diuretics fast or slow?
Osmotic diuretics cause isotonic/hypotonic or hypertonic dehydration??
Osmotic diuretics are used for which type of oedema?
Osmotic diuretics can be used to treat acute renal failure. T/F
HCO3 reabsorption occurs primarily in which part of the kidneys?
Carbonic anhydrase inhibitor
What type of drug is acetazolamide?
What is the effect of CA inhibitors?
CA inhibitors are used for generalized oedema. T/F
The thick ascending limb is impermeable to what?
Frusemide is an example of what diuretic?
Na/K/2Cl symporter, thick ascending limb
Frusemide inhibits which pump and in which segment?
Which ions are reabsorbed into the blood at the thick ascending limb by the recycling of potassium ions back into the lumen?
Digoxin, aminoglycosides, warfarin, ACE inhibitors
What drugs are contraindicated with loop diuretics?
Acute pulmonary oedema, CHF, liver cirrhosis, renal failure, hypertension
Loop diuretics are used for what?
Distal convoluted tubule
Hydrochlorothiazide acts where?
Thiazides enhance the reabsorption of which ion?
Generalized oedema, hypertension, diabetes insipidus
Thiazides are used to treat what?
Loop diuretics, thiazides
Hypokalaemia is associated with which diuretis?
Digoxin, oral hypoglycaemic agents
Thiazides interact with which drugs?
What are potassium-sparing diuretics?
Congestive heart failure
Spironolactone is used novelly to treat what?
potassium-sparing diuretics, ACE inhibitors
Severe hyperkalaemia can be caused by combination of which drugs?