Vaccine age 0-1yr
DTaP=diphtheria, tetanus toxoids, acellular pertussis
Hep B-(Energix-B, Recombivax HB)
IPV, IPOL, Salk Vaccine
Hib (Haemophilus influenza type b)
Hep A (Havrix, VAQTA)
influenza (Fluvirin, Fluzone) strains from a and b
DTaP + IPV = Kinrix
Kinrix + Hib = Pentacel
Kinrix + Hep B = Pediarix
Hib + Hep B = Comvax
Rotateq (live) given oral drops x 3 (2007)
pneumonia for infants (killed) PCV- pneumococcal conjugate vaccine. (Prevnar)
Killed vaccines are administered intra muscularly.
Live Vaccines are administered sub-q, oral or by nasal inhalation
immunity provided by the body producing its own antibodies against a particular antigen; results from exposure to the antigen via infection or vaccine
an immunity resulting from antibodies that are conveyed naturally through the placenta to a fetus or artificially by injection of a serum containing antibodies
Protection that is inherited and is present at birth to fight off infection
Immunity that requires some deliberate action, such as a vaccination, to achieve exposure to the potentially harmful antigen
Example of active natural immuntiy
Contract disease and produce memory cells.
Blood- B-lymphocytes (5 IG's)
Eample of active artificial immunity
Receive a vaccination and produce memory cells
Example of passive natural immunity
Receive maternal antibodies through placenta or breast milk.
Example of passive artificial immunity
Receive antiserum with antibodies from another host.
Transfusion of IG's
Synthetic interferon Alpha (Referon)used for Pt's with Kaposi carcinoma (hiv skin cancer).
Synthetic interferon Beta (Anovex, Betaseron) used to treat MS.
Synthetic interferon Gama (Cyclosporine) used for organ transplant Pt's and RA Pt's.
Interferons: Alpha, Beta, Gama
Alpha made by: White Blood cells
Beta made by: Fibroblasts
Gama made by: T Lymphocytes
Live Vaccine we no longer use
Vaccine age 12-15 month
MMR given sub Q
Varivax given Sub Q
Vaccine for Adults
Pneumonia- PPV- pneumococcal polysaccharide vaccine (Pneumovax) age 60 +
shingles (Zoster) vaccine age 60+
human papillomavirus vaccine (Gardasil) age 11-26
meningococcal vaccine -2 types MCV and MPV
MCV (Menactra) given IM
MPV (Menomune) given Sub Q
(NOTE: antibodies bind to specific antigens in a lock-and-key fashion, forming an antigen-antibody complex. Antibodies are a type of protein molecule known as immunoglobulins (Igs).) There are 5 classes of innunoglobulins which will be listed on individual flashcards; they are IgG, IgA, IgM, IgE, IgD
found in blood. recognies bacteria, viruses, and toxins. It can also activate complement. Provide long term immunity after vaccination. Crosses the placenta. Passive immunity (infant).
Found in secretions of the body such as breast milk, sweat, tears, saliva and mucus. Prevents pathogens from entering the body.
Found in blood. Very large. Primarily binds to antigens on food, bacteria or incompatible blood cells. Activates complemnt. Produced first in infants.
Found in mast cells or basophils- involved in triggering allergic reactions.
Found as receptors on B-lymphocytes. Small amount in BLOOD. Signal when the young B cells in the spleen are ready to be activated.
Helper T cells
T cells that help the immune system by increasing the activity of killer cells and stimulating the suppressor T cells. Also called CD4 T cells
Memory T cells
Have receptors for specific antigens due to prior exposure from past infection or vacination. Are capable of mobilizing and cloning themselves providing a faster response time if/when infection is encountered again.