| Term | Definition |
|---|
| dibenzoxepin tricyclics | antidepressant, doxepin |
| ethanolamines | marked sedation, anticholinergic; diphenhydramine |
| ethylenediamines | NO cholinergic activity, GI problems common; pyrilamine |
| alkylamines | most potent in low doses, CNS stimulation (used in daytime); chlorpheniramine |
| piperazines | moderate sedation, teratogenic, 70% excreted unchanged; meclizine |
| phenothiazines | anticholinergic, prominent sedation, best antiemetic; promethazine |
| piperidines (1st generation) | moderate sedation, antiemetic; phenindamine |
| piperazines (2nd generation) | few side effects, Citirizine |
| piperidines (2nd generation) | few side effects, arrhythmias; loratadine, fexofenadine, desloratadine |
| sulfonylureas | tolbutamide, glipizide |
| meglitinides | repaglinide, nateglinide |
| biguanides | metformin |
| glucosidase inhibitors | acarbose, miglitol |
| thiazolidinediones | pioglitazone, rosiglitazone |
| MOA-sulfonylureas & meglitinides | increase insulin release from beta cells (can cause hypoglycemia; don't give to pts on insulin therapy) |
| MOA--biguanides | increase insulin action in peripheral tissues (can cause GI disturbances) |
| MOA--glucosidase inhibitors | impair carbohydrate digestion and absorption (can cause farting, GI cramping, diarrhea) |
| MOA--thiazolidinediones | activate PPARy (can cause peripheral edema, cardiac toxicity, hypoglycemia) |
Combine with other sets
Share on Facebook
Share on MySpace