Pharmacology Ch. 1 - Intro

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Pharmacology 6th Edition - An Introduction - Chapter 1 - Intro

Adverse Effect

General term for undesirable and potentially harmful drug effect.

Agonist

Drug that binds to a receptor and activates a physiological response or drug action

Antagonist

Drug that binds to a receptor and inteferes with other drugs or substances from producing a drug effect.

Chemical Name

Name that defines the chemical composition of a drug

Contraindications

Situations or conditions when a certain drug should not be administered

Controlled Substance

Drug that has the potential for abuse and thus is regulated by the law

Dose

A measurement of the amount of drug that is administered

Drug Indications

Intended or indicated uses for any drug

ED50

Effective dose 50, or dose that will produce an effect that is half of the maximal response.

Generic Name

Nonproprietary name of drug

LD50

Lethal dose 50, or dose that kill 50 percent of the laboratory animals tested

Mechanism of Action

Explanation of how a drug produces its effects

Nonprescriptions, over-the-counter (OTC) drug

Drug that can be purchased without the services of a physician

Pharmacology

Study of drugs

Potency

Measure of the strength, or concentration, of a drug required to produce a specific effect

Prescription Drug

Drug for which dispensing requires, a written or phone order that can only be issued by or under the direction of a licensed physician

Receptor

Specific cellular structure that a drug bings to and that produces a physiological effect.

Side Effect

Drug effect other than the therapeutic effect that is usually undesirable but not harmful.

Site of Action

Location within the body where a drug exerts its therapeutic effect, often a specific drug receptor.

Therapeutic Effect

Desired drug effect to alleviate some condition or sympton of disease.

Therapeutic Index (TI)

Ratio of the LD50 to the ED50 in animal studies.

Toxic Effect

Undesirable drug effect that implies drug poisoning; can be very harmful or life-threatning.

Trade Name

Patented propietary name of a drug sold by a specific drug manufacturer; also referred to as the brand name.

Scedule 1

Drugs with high abuse potential and no accepted medical use (Heroin, hallucinogens, marijuana; these drugs are not to be prescribed)

Scedule 2

Drugs with high abuse potential and accepted medical use (Narcotics [morphine & pure codeine], cocaine, amphetamines, short-acting barbiturates, nabilone; no refills without a new written prescription from the physician.

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