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Frank Starling Law

The greater the stretch of the cardiac muscle cell, the greater the force of contraction.

Frank Starling Law is aka as Length-tension relationship

Where length refers to the stretch of the myocardial cell and tension refers to contraction

Preload

length to which a myocardial cell is stretched and measured clinically as pulm. wedge press, central venous press, ventricular end-diastolic press or ventricular end-diastolic volume

As preload increases cardiac performace (eg; SV, CO) will increase ______

a certain physiologic limit

What increases the preload?

Atrioventricular valve regurg, semilunar valve regurg, and congential heart defect shunts (ASD,VSD, PDA)

Increase in preload is associated with

Chamber dilatation

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