| Term | Definition |
| descant | discussion |
| descry | to discover by observation |
| desecrate | to change from sacred to profane |
| desiccate | dry, dehydrate |
| desist | to stop doing something |
| desultory | disconnected |
| dichotomy | a division into two |
| dictum | a positive statement |
| didactic | intended to instruct |
| diffident | shy |
| digress | to stray away from subject |
| dilate | swell, distend, expand |
| diligent | industrious; with an energetic effort |
| disconcert | confuse, upset, to disturb |
| disconsolate | cheerless, hopelessly sad |
| discountenance | to look with disfavor on |
| discursive | passing from one topic to another; rambling |
| disdain | contempt, scorn |
| disparage | to belittle |
| disseminate | to spread abroad as if sowing seed |
| dissident | disagreeing |
| dissipate | to scatter wastefully |
| dissonance | discord |
| diurnal | daily |
| diverse | various; several |
| divest | to rid or free from; to sell off |
| docile | easily taught, led, or managed |
| doggerel | verse that is loosely styled; poorly written |
| dogmatic | arrogant; unyielding |
| dolorous | mournful |
| dormant | inactive; not actively growing or functioning |
| dour | stern, harsh; gloomy |
| dregs | the most undesirable part; leftovers |
| dulcet | pleasing to the ear |
| dudgeon | sullen resentment or anger |
| ebullition | boiling over |
| eclogue | a pastoral poem; country poem |
| edify | to enlighten |
| effete | worn out |
| efficacious | potent to produce an effect |
| effigy | a dummy |
| effrontery | shameless or boldness |
| egregious | outstanding |
| elicit | to draw out or forth |
| emaciated | haggard |
| emanate | to issue forth |
| emollient | making soft or supple |
| empirical | experimental |
| emulate | to excel or imitate |
| duplicity | deception |