| Term | Definition |
|---|
| Choroid Plexus | a vascular plexus of the cerebral ventricles that regulate intraventricular pressure and secrete CSF |
| subarachnoid space | CSF flows out through the foramina of Lushka into this area |
| Virchow-Robin Spaces | csf that has left through the foramina of Lushka extends deep into the cerebral cortex in extensions of the subarachnoid space along these special blood vessels |
| arachnoid villi | visible only microscopically, these structures are found in clusters and appear as herniations of the arachnoid membrane. They reach through the dura and into the lumen of the suerior saggital sinus and other venous structures. |
| bulk flow | term for the one way flow of csf from the subarachnoid space into the venous blood |
| rate of CSF formation | .35ml/min or 500ml/day |
| CSF vs blood plasma | has less potassium, bicarbonate, calcium and glucose. A lower pH , and higher concentrations of magnesium and chloride |
| Capillary Filtration and Active Epithelial Secretion | The formation of CSF in the choroid plexus seems to be a combination of these two mechanisms |
| Paul Erlich | Discovered of intravenous injection of dyes resulted in the staining of tissues in most organs but not the brain. |
| difference between brain vessel capillaries and other tissue capillaries | They ahave tight junctions between capillary endothelial cells, they are surrounded and encased in the glial foot processes of astrocytes, and the mitochondria are more numerous in the endothelial cells of this tissues capillaries. |
| cusion effect of CSF | This material provides a cussion to protect the brain from impact with the skull interior when struck or moved suddenly. It also reduces the relative brain weight in air from 1400g to 50g. |
| red or white blood cells | healthy CSF does not contain any of these. |
| high protein content | this in measues greater than 500mg/dl is usually a manifestation of a block in the spinal subarachnoid space by a tumor or other compressive lesion |
| Lumbar Puncture | An ordinary measure of CSF Pressure |
| 65-195mm CSF or 5-15mm HG | the normal pressure of CSF in the CNS |
| Monro-Kellie Doctrine | An increased volume of any one of the contents of the CNS must be accompanied by a decrease of another component or there will be a marked increase in intracranial pressure. |
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