Chapter 18

Created by map142 

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present peptide antigens to T cytotoxic lymphocytes

HLA-A/B/C

ligands for NK cell receptors

HLA-E/G

only MHC II gene to have 4 functional genes

HLA DRB

antigens normally found in large amounts only on surface of APC and present peptides to T helper

HLA-DR/DQ/DP

antigens found inside the cells and function in loading peptides

HLA-DM/DO

chromosome number and crossing over rate for eleven major MHC genes

6/2

prevent activation of T CELLS and are the primary drugs that are used to prevent the rejection of organ allografts

cyclosporin/FK-506

privileged site that produces TGF-beta

cornea

privileged site that express low levels of class I and II HLA antigens

liver

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