| Term | Definition |
| oaf | stupid, awkward person |
| obdurate | Stubbornly persistent in wrongdoing , obstinate |
| obeisance | Bending the head or body or knee as a sign of reverence |
| obelisk | tall column ending in a pyramid |
| oblique | neither parallel nor perpendicular |
| obliterate | Do away with completely, without leaving a trace |
| obloquy | State of disgrace resulting from public abuse |
| obsequious | Attentive in an ingratiating or servile manner |
| obsequy | funeral ceremony |
| obsidian | black volcanic rock |
| obstetrician | physician specializing in delivery of babies |
| obstreperous | Boisterously and noisily aggressive and defiant |
| obtrude | Push to thrust outward,Impose something unpleasant (inflict), foist |
| obviate | make unnecessary, get rid of |
| occident | west ,western hemisphere |
| occlude | Block passage through |
| occult | Hidden and difficult to see, mysterious, secret |
| oculist | A medical doctor specializing in the diagnosis and treatment of diseases of the eye |
| odious | detestable, hateful |
| odium | State of disgrace (o) and hate resulting from detestable behavior |
| odoriferous | Having a natural fragrance, sweet smelling |
| odyssey | a long wandering and eventful journey |
| officious | meddling; excessively forward in offering one's service |
| oligarchy | government by a privileged few |
| onerous | burdensome, hard to bear |
| onomatopoeia | using words that imitate the sound they denote |
| onus | An onerous or difficult concern ,responsiblity |
| opalescent | Having a play of lustrous rainbow colors |
| opiate | a narcotic drug that contains opium or an opium derivative |
| opportune | timely; well-chosen |
| optometrist | a person skilled in testing for defects of vision in order to prescribe corrective glasses |
| opulence | Wealth as evidenced by sumptuous living |
| opus | a musical work that has been created |
| oracular | obscurely prophetic or divine |
| ordain | decree or command; grant holy orders; predestine; install as a minister, priest, or rabbi; N. ordainment; CF. ordination |
| ordinance | decree |
| ordination | act of ordinance |
| orient | familiarize, Adjust to a specific need or market |
| osseous | Composed of or containing bone |
| ossify | Cause to become hard and bony |
| ostracize | Expel from a community or group, Avoid speaking to or dealing with |
| oust | boot out |
| overt | Open and observable; not secret or hidden |
| ovoid | An egg-shaped object |