Top 200 Drugs

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35 terms · drugs; PCL

TRAMADOL

TC: analgesic

PC: Partial Opiate Agonist, NMDA receptor antagonist
SE: dizziness/drowsiness [ALCOHOL CAN INCREASE RISK OF SEIZURES]
serotonin syndrome: S&S: large amount of serotonin, tremor, N&V, dizziness, excessive sweating, jittery, hyperthermia (HOT), HTN
Drug Interaction: SSRIs, St.John's Wort, opioIds, alcohol [respiratory depression], hypnotics (ambien), narcotics (morphine codeine), cyclobenzaprine - excessive drowsiness
withdrawl symptoms can occur if d/c abruptly
CAN TAKE IBUPROFEN AND APAP, ICE
CIV in NM
Use for pain > 4
max dose: 400 mg/day IR, 300mg/day ER

TC: OPIOID ANALGESIC

OXYCODONE/APAP (PERCOCET, ENDOCET, ROXICET) CII

HYDROCODONE/APAP (VICODIN, LORTAB) CIII

PROPOXYPHENE-N/APAP (DARVOCET-N) CIV

APAP W/CODEINE (TYLENOL #3) CIII

OXYCODONE CR (OXYCONTIN) PC: OPIATE AGONIST NMDA RECEPTOR ANTAGONIST
ER ONLY; CII

PC: OPIOID AGONIST W/APAP COMBO

BBW: contains APAP max 3g/day- acute liver failure
Do not use w/APAP (overdose, hepatotoxicity)
Pharmacologic for constipation: OTC stool softener Docusate
Non-Pharmacologic for constipation: Prune juice if they don't have DM, increase fiber, H2O, exercise
Alcohol avoid while taking opioids (drowsiness)
pain scale: 0-10 if over of 4 then no self-care
max dose of APAP: 3g/day
COMMON SE: upset stomach (not an allergy), dizziness, drowsiness, lightheadedness
IR VS. ER
OxyContin ER - sometimes patients are on both, the ER is used as maintenance for pain pt. will take on scheduled basis IR is more for breakthrough pain (like cancer)

BENZODIAZEPINES

CLONAZEPAM-long acting
DIAZEPAM - long acting
LORAZEPAM - medium acting
ALPRAZOLAM - short acting

long term (> 30 days) use avoid abrupt cessation
drink in moderation and not in excess
CIV: I would give a 3 day supply if can't get a hold of the doctor
short acting vs long acting: short acting are the ones that are abused (xanax) than long acting
CNS effects- extreme dizziness to stop breathing when taken with alcohol
interaction w/St.John's Wort [CYP interaction it decreases the effectiveness of lorazepam]

TC: antianxiety agent

LORAZEPAM

PC: benzodiazepines medium half-life (10-15 hours)
CIV
interaction with St.John's Wort (CYP interaction it decreases the effectiveness of lorazepam)

Do not stop abruptly if have been taking for more than 30 days - taper off slowly b/c of w/d effects: agitation, anxiety, insomnia, convulsions

Drink in moderation- CNS could range from extreme dizziness to stop breathing

common SE: drowsiness and dizziness (muscle relaxants, sleep aids, benadryl)

medium 1/2 life: benzos that are short-acting are more likely to be abused b/c they are better at giving a high

TC: muscle relaxant

CYCLOBENZAPRINE (FLEXERIL)

CARISOPRODAL (SOMA) - CIV

PC: CNS skeletal muscle relaxant

use pain scale (0-10)
MAX DOSE; 30mg/ day
Interactions:
RX- CNS depressants (range from excessive dizziness to stop breathing , tramadol (seizures, increased risk of stopping breathing)
OTC- Benadryl excessive drowsiness
ETOH- excessive drowsiness, blurred vision

SE: dry mouth (sugarless candy/gum) > 2 day
drowsiness
do not become overheated in hot weather or exercise- heat stroke

TC: NSAIDs

IBUPROFEN (MOTRIN)
NAPROXEN (NAPROSYN)
MELOXICAM (MOBIC)
CELECOXIB (CELEBREX) PC: cyclooxygenase 2-inhibitor (COX2 Inhibitor)

BBW: CVD risk- increase risk of serious cardiovascular thrombotic events, MI, stroke, increase w/duration and patient w/CVD at higher risk
GI risk; increase risk of serious GI risk - bleeding, ulceration, perforation of the stomach or intestines elderly increased risk

eliminated by renal system- NSAIDs
APAP- eliminated in liver

dialysis - no NSAIDs
ETOH - increase the risk of stomach bleeding (tarry stools, vomit (coffee grounds), ASA and NSAIDs

SE: dizziness, drowsiness, full glass of water

category D in 3rd trimester

max doses:
ibuprofen - 3200 mg total daily, 1200mg (children)
naproxen - 1500mg
mobic- 15mg/day
celebrex - 600mg

upper bleed- bloody vomit, black tarry stools
lower bleed- bloody stools, coffee ground vomit

PC: SSRIs

CITALOPRAM (CELEXA)
ESCITALOPRAM (LEXAPRO)
SERTRALINE (ZOLOFT)
PAROXETINE (PAXIL)
FLUOXETINE (PROZAC)

TC: ANTIDEPRESSANT

BBW: increase risk of suicide in children and adoloscents
signs of depression - withdrawing, talking down about themselves, lack of interest, irritability - let patients know or what to look for- some patients who take this find the confidence to commit suicide
Do not take MAOIs (selegiline) b/c of serotonin syndrome [ excess of serotonin in the blood, severe anxiety, hyperthermia, tachycardia, HTN]

ETOH use: in both antidepressants and antipsychotics, drink in moderation- 1 drink (4oz)/day [women], 2 drinks (4oz)/day [men]
alcohol decreases efficacy of the antidepressants and antipsychotics (makes less effective), ADME ineffective, alcohol is a depressant

OTC: St.John's Wort: competing p450 can get toxic effect of SSRI causing serotonin syndrome
increase risk of bleeding (coumadin have to adjust INR), NSAIDs

onset of action: 4 weeks to see benefit

Common SE: drowsiness (take at HS), fluoxetine can cause insomnia so if not sleeping switch to morning
nausea and diarrhea- take with food or snack
SEXUAL SE: decreased ability; erectile dysfunction
SERIOUS SE: paradoxical effect- suicidal thoughts increase risk

tramadol can't be used b/c it will work against antidepressant (SSRIs) and have additive effects

TC: DEPRESSION

TRAZODONE (Desyrel)

PC: NE & DA reuptake inhibitor

BBW: increase risk of suicidal thinking
should not be used in children/teenagers

interactions: SSRIs b/c of SE
anticoagulants (increase risk of bleeding)
diuretics (increase risk of blood sodium)

take with meal or snack
avoid alcohol b/c of drowsiness, dizziness, blurred vision
priapism
SERIOUS SE: stiff muscles, fever, confusion

TC: ANTIDEPRESSANT

AMITRIPTYLINE (Elavil)

PC: NE, DA AND SEROTONIN REUPTAKE INHIBITOR (TCA)

BBW: increase risk of suicidal thoughts or actions in children, teenagers, and young adults
be mindful or monitor symptoms of worsened depression, suicidal thoughts or changes in behavior

do not use if using antihistamines
may cause dizziness, drowsiness, or blurred vision
avoid drinking alcohol b/c could increase drowsiness
sun sensitivity

TC: SEDATIVE

ZOLPIDEM (AMBIEN) VS. ZOLPIDEM ER (AMBIEN CR)

PC: SELECTIVE ALPHA-1 BENZODIAZEPINE RECEPTOR AGONIST

indication: IR- to fall asleep IR = RR
ER - to stay asleep

CIV
drowsiness interactions: Rx, OTC, ETOH
OTC: Benadryl, melontonin, NYQUIL
ETOH: CNS effects, range from extreme dizziness to stop breathing
High meals slows absorption (fat meals)

sleep hygiene: bad habits before sleep, only use bed for bedroom activity, no TV, reading, working in bed, temperature comfortable to sleep in, develop ritual or habit before bedtime, avoid overstimulation (loud music)

TC: ANTIPSYCHOTIC

QUETIAPINE (SEROQUEL)

OLANZAPINE (ZYPREXA)

ARIPIPRAZOLE (ABILIFY)

PC: 2ND GENERATION ANTIPSYCHOTIC

BBW: increase mortality w/elderly [monitor bp]
CVD issues and infection
increases risk of death
CVD- monitor bp, cholesterol, respiratory rate and HR

BBW2: increase risk of suicidal thoughts in children, adolescents and young adults

synergism w/antidepressants- 2 drugs produce an effect that is greater than the effects of the individual drug

SE: drowsiness, weight gain (quetiapine), increased lipids (monitor), increase risk of DM but don't d/c, dry mouth, hypotension, sexual SE (decreased inability)

*Alcohol makes antipsychotics less effective drink in moderation
*uncontrolled DM = NO USE Controlled DM = OK to USE

SERIOUS SE: muscle issues, dyskinesia (uncoordinated movements), look out for it if its occurring SWITCH to another drug

GENERAL ANTIBIOTICS SE

Diarrhea
sun sensitivity
BCP (back-up)
N&V
stay hydrated
antacids (separate by 2 hours)
finish medication even though you may feel better

PEN VK - empty stomach, no sun sensitivity

BBW- cipro, levaquin

PC: TRIAZOLE

FLUCONAZOLE (DIFLUCAN)

TC: ANTIFUNGAL

NO APAP SO TAKE NSAIDs
BCP, Plavix may decrease effectiveness
2 hours before PPI

indication: yeast infections, thrush, mennigitis prophylaxis

COMMON SE: dizziness, change in taste, diarrhea, HA, stomach pain, N&V, rash (if worsens d/c)
SERIOUS SE: hepatic injury (dark urine, jaundice)

anticoagulants, benzos b/c this med may increase their SE

tell if going to have dental/medical emergency care or surgery

PC: Cephalosporin

CEPHALEXIN (KEFLEX)

TC: CEPHALOSPORIN ANTIBIOTIC

Indications: otitis media, gram (-), respiratory tract infections, UTI, skin infections (most common)

decreases effectiveness of vaccines
MOA: interferes w/ cell wall of bacteria causing it to rupture

Patient INFO: w/ or w/o food

SE: mild diarrhea, more serious pseudomembranous colitis (blood and pus in diarrhea), dizziness

DM patients may cause urine glucose to read wrong

PC: SULFONAMIDE COMBO

SULFAMETHOXAZOLE AND TRIMETHOPRIM (BACTRIM, BACTRIM DS)

TC: ANTIBIOTIC

Indication: acute otitis media, UTI, traveler's diarrhea, chronic bronchitis, pneumonia

C/I: pregnancy, child <2y/o- hepatic damage

PI: d/c at first sign of rash
careful in AIDS patients increase advance reactions
common adverse reactions- GI and skin rashes
allergies- Sulfonamide (sulfa) drug
anticoagulants increase bleeding
take with a full glass of H2O, maintain hydration, sun sensitivity, mild diarrhea, pseudomembranous colitis, appetite loss, N&V

DM: check blood glucose

PC; MACROLIDE

AZITHROMYCIN (ZITHROMAX)

TC: MACROLIDE ANTIBIOTIC
indications: acute otitis media,HIV pneumonia, sinusitis, STD

PI; with or w/o food
TAKE ANTACIDS 2 HOURS AFTER TAKING ZITHROMAX
if you have liver problem don't take it
anticoagulants: SE could be increased b/c of zithromax
tell dr./dentist if going to have emergency care or surgery

COMMON SE: drowsiness, dizziness, lightheadness, mild diarrhea, sun sensitivity
SEVERE SE: hepatotoxicity, myasthenia gravis, cardiac QT prolongation (antiarrhythmic)
[ANGIODEMA, JAUNDICA-RARE}

PC: AMINOPENICILLIN, BETA-LACTAMASE INHIBITOR

AMOXICILLIN AND CLAVULANATE XR
(AUGMENTIN XR)

TC: ANTIBIOTIC

Indications: otitis media, bacterial sinusitis, pneumonia, skin infections, UTIs

C/I: patient allergic to penVK, hepatic injury, severe renal impairment
fatal anaphylactic reaction in patients w/ penvk allergies
anticoagulants increase bleeding
DECREASED BCP EFFECTIVENESS
take at start of meal, do not crush or break swallow whole

SE: dizziness (alcohol increases effect), mild diarrhea, N&V, psudomembraneous colitis, has NA+ in it, tooth discoloration (rare, children)

PC: FLUROQUINOLONE

CIPROFLOXACIN (CIPRO)

TC: FLUROQUINOLONE ANTIBIOTIC

BBW: tendonitis and tendon rupture- all ages even more of a risk in elderly (> 60 y/o), patients taking corticosteroids and in patients w/kidney, heart and lung transplants
myasthenia gravis- may exacerbate muscle weakness in persons with mg so avoid use

indications: UTI, gram (-), lower respiratory tract infections, skin infections, typhoid fever

SE: take with food or crackers, NO MILK b/c of calcium binding so don't use milk
ANTACIDS: take 2 hours before or 6 hours after CIPRO
RARE SE: crystaluria- maintain hydration

TC: penicillin sensitive staphylococci, streptococci, pneumococci

PENICILLIN VK (VEETIDS)

TC: ANTIBIOTIC

PATIENT INFORMATION
BCP EFFECTIVENESS DECREASES
anticoagulants effectiveness decreases
best absorbed when taken on empty stomach (1 hour before/2 hours after meal)

Do not take if allergic to amoxicillin, cephalosporin, antibiotics

COMMON SE: black hairy tongue, irritation in mouth or throat, N&V, diarrhea (mild)
SEVERE SE: pseudomembranous colitis, caution in asthma patients

PC: FLUOROQUINOLONE

LEVOFLOXACIN (LEVAQUIN)

TC: FLUOROQUINOLONE ANTIBIOTIC

BBW: tendonitis and tendon rupture is increased in all ages further risk in alder patients, patients taking corticosteroids, patients with kidney, heart, or lung transplants
myasthenia gravis- may exacerbate muscle weaknes in person should avoid use

Indications: community acquired pneumonia, gram -, UTI, skin infections, anthrax

PI: maintain hydration (crystaluria), antacids separate by 2 hours

COMMON SE: dizziness, mild diarrhea, constipation, sun sensitivity
SEVERE SE: hepatotoxicity, QT prolongation, antiarrhythmia (MEDS) this could increase
insulin or oral DM drugs- risk of high or low blood sugar may be increased
anticoagulants (warfarin)- increased bleeding
corticosteroids (tendon problems may increase)
NSAIDs, theophylline b/c serious SE seizures increase

PC: BROAD SPECTRUM GRAM -/+

DOXYCYCLINE (VIBRAMYCIN)

TC: TETRACYCLINE ANTIBIOTIC

indications: gram -, atypical infections and chlamydia
Pregnancy D
SE: pseudomembranous colitis, sunlight sensitivity, tooth discoloration, mild diarrhea, loss of appetitie

PI: with or w/o food, if stomach irritation eat
take antacids 2 hours after medication, multivitamin
drink plenty of fluids to avoid throat irritation
BCP MAY NOT WORK AS WELL USE BACK
NAUSEA AND VOMITING

PC: REPLICATION INHIBITOR DNA POLYMERASE

VALACYCLOVIR (VALTREX)

TC: ANTIVIRAL

Indications: genital herpes, chicken pox, shingles

MOA: stops viral replication
NSAIDs may harm kidney

MAINTAIN HYDRATION

COMMON SE: drowsiness, dizziness, fainting, alcohol, sun senstivity, diarrhea, HA, N&V

oral contraceptives

BBW: cigarette smoking increased risk of smoking

be mindful of sharp chest pain, SOB b/c of pulmonary embolism (clot)
OCP that can help decrease edema= drospirenone (diuretic)
call HCP if pain in calf, heaviness in chest, sudden severe HA, weakness/numbness in legs sudden partial/complete loss of vision = clot

high estrogen = irritability, acne, HA, N&V, fluid retention, breast tenderness, vaginal bleeding (spotting)

smoking increase clot risk after 35 y/o

pre-existing conditions: HTN, DM2, hyperlipidemia, oesity, liver failure, inherited risk - risk of clotting

don't take St. Johns Wort

RISENDRONATE SODIUM (ACTONEL)

ALENDRONATE (FOSAMAX)

PC: BISPHOSPHONATE

TC: OSTEOPOROSIS AGENT

PI: abnormalities of the esophagus may use in caution w/upper GI disease

RR: take 30 min before 1st meal or drink then can eat 30 minutes after

ER: take after breakfast DO NOT take on empty stomach (Atelvia)

take while in upright position (sitting or standing) w/full glass of water avoid laying down for at least 30 minutes before taking other meds

SE:
hypocalcemia- we need to make sure the patients Ca+ levels are normal before starting meds (increase calcium, eat dairy, broccoli, almonds or supplements)

1000mg for men and women, >50 y/o 1500mg

non-pharmacologic: weight barring exercise

Antacids 2 hours after, can take vitamins, NSAIDs, ASA 30 minutes after

SE: COMMON: esophageal irritation, jaw osteonecrosis= not common jaw bone b/c weakened more likely w/mouth infection or undergoing oral surgery

* tends to be hard on the esophageal tissue so if they lay back down then the risendronate solution is laying on the mucosa on the lining of esophagus and over time can irritate it so can food

*SR b/c it is easier to take meds w/food
*need normal blood Ca2+ levels: calcium supplement vitamin D helps absorb calcium

pregnancy C

NUVARING (ETHINYL ESTRADIOL AND ETONOFESTREL)

PC MONOPHASIC HORMAL CONTRACEPTIVE

TC: CONTRACEPTIVE

if it has been less than 3 hours rinse it off in lukewarm water and reinsert but if it has been more than 3 hours insert a new one or don't insert it and menstrate

can have sex and use a tampon
needs to be refrigerated
changing from OCP - Nuvaring; insert ring use back up method for 7 days
as long as patients insert ring when menstrating then protected

miconazole nitrate (yeast infection) decreases effectiveness of BCP

DIRECTIONS TO INSERT RING:
wash hands and dry
choose a comfortable position (lying down, squatting, standing with one leg up)
hold ring between your thumb and index finger and press the opposite sides of the ring together
gently insert and push the folded ring into the vagina as far as comfortably possible
you don't have to have it in the exact position for it to work
you should not feel the ring once inserted if you doit is not inserted far enough into the vagina
if it comes out of place use finger to push back up you can not put it too far up vagina b/c cervix will block
should be left in for 3 weeks then removed

DIRECTIONS TO REMOVE THE RING
wash and dry hands
again find comfortable position
loop your finger through the ring and gently pull it out
discard ring in trash DO NOT FLUSH
wait 7 days before inserting a new ring

first time using contraceptive insert when menstrating and will be protected from then on

SE same as premarin and OCP

LISINOPRIL
ENALAPRIL
BENZEPRIL

PC: ACE INHIBITORS (Angiotensin Converting Enzyme Inhibitor)

TC: antihypertensive

BBW: Pregnancy D (2nd and 3rd trimester) injury or death to the fetus

C/I: angiodema (vascular leakiness)- swollen face and lips can be hereditary, idiopathic, past history

SE: Cough (nonproductive) switch to ARB
PI: angioedema
hypotension
hyperkalemia (high potassium)- no K+ supplements
salt substitutes that have potassium when people are trying to shake the salt let them know it says potassium chloride

VALSARTAN
OLMESARTAN

PC: ARB (Angiotensin Receptor Blocker)

TC: antihypertensive

BBW: pregnancy D
PI: hypotension (dizziness)
hyperkalemia: no K+ supplements
salt substitute some have K+ in it

METOPROLOL TARTRATE
METOPROLOL SUCCINATE (TOPROL XL)
ATENOLOL (TENORMIN)
CARVEDIOLOL (COREG)

PC: BETA BLOCKERS

TC: ANTIHYPERTENSIVE

BBW: Ischemic heart disease; abrupt cessation of therapy may cause angina pectoris or MI when patients taper off over a period of 1-2 weeks even in patient with HTN d/c gradually
Major surgery: pt. should not d/c but PCP should know if do need to d/c 1-2 weeks taper off
Bronchospastic Dx: asthma COPD- caution and monitor w/use
DM & hypoglycemia: if experience low blood sugar but patient can't tell (shaky, tired, dizzy, confused, SWEATING only symptom that will be seen

PHEOCHROMOCYTOMA: tumor in the adrenal glands secretes adrenaline in an uncontrolled fashion
THYROTOXICOSIS: thyroid storm, hyperthyroidism, HR increased

C/I: if someone already has a compromised heart be cautious HR < 45 bpm systolic >100 or HR low bp, bradycardia

should be advised to regularly and continuously take as directed with or immediately following meals or with meals [bioavailability ER, small intestine better absorption]
DO NOT D/C ABRUPTLY
hypotension: lightheadedness, dizziness, from a sitting to standing position- resolves (15-30 seconds) be careful getting up; driving car tasks requiring alertness
concomitant use of clonidine- stop beta-blocker 1st and then stop clonidine
depression and fatigue: 1st couple weeks patient doesn't feel well
ER TABLET: don't crush, swallow whole, no chewing, sometimes shell will be in the toilet

take 4 hours before next dose if missed dose or rule of thumb: take as soon as you remember as long as it is NOT the same day that they have taken another dose

TRIAMTERENE/HCTZ (MAXZIDE)

PC: POTASSIUM SPARING DIURETIC/THIAZIDE DIURETIC COMOBO

TC: DIURETIC

C?I: anuria and oliguria
PT INFO
sunlight
OTC products (appetite suppression and cough and cold)
sulfonamide allergy
hypotension
etoh intake
hydration
take with or w/o food; if stomach upset take WF
this medication will increase the amount of urination when 1st start taking take before 6pm so it will not disrupt patient sleep
hypokalemia- low K+
hypomagnesemia

HCTZ

PC: thiazide diuretic
potassium wasting

TC: diuretic

C/I: anuria, oliguria
PT INFO (same as lasix)
sunlight
OTC products (appetite suppression and cough and cold)
sulfonamide allergy
hypotension
hypokalemia- leg cramps; help body retain K+; low K+
hypomagnesemia- if low in K+ the low in Mg
ETOH intake
hydration
this medication increase the amount of urination when first start taking try to take before 6pm so it will not disrupt sleep
increase blood sugar

FUROSEMIDE

PC: LOOP DIURETIC

TC: DIURETIC (POTENT)

BBW: profound diuresis, H2O and electrolyte depletion - draw labs

C/I: can't use it fi patient has anuria (no urine) and oliguria (some urine)
PT INFO
sunlight (photosensitivity, increase sunburn)
sulfonamide allergy- if allergic to sulfa NO LASIX
hypotension- postural HTN
potassium supplements- lasix works in the loop of henle it wastes K+ at high rates; you want them on K+ supplements
hypokalemia (muscle weakness, aches)
hydration- N&V - drink fluids, 6-8 glasses of 8oz. of H2O it is a pain
6 hours before bedtime to prevent going to pee at night
ETOH intake- dehydration

NIACIN ER

PC: VITAMIN

TC: HYPERLIPIDEMIC

C/I: known bleeding- aerial, peptic ulcer hepatic dysfunction

PT. INFO
OTC/RX- max dose 6g/day (hyperlipidemia)IR, maintenance dose (2000mg/day) ER
ER tab- do not crush, chew or break tabs, swallow whole
FLUSHING- hot redness in face - if released slower
ER- take an ASA, NSAIDs take it 1/2 hour before niacin
non-pharmacologic: no hot liquids/drink cold liquids, cold compress, cold shower, separate exercise

same as vitamin B3
concomitant use of anticoagulants (increase bleeding)

FENOFIBRATE (TRICOR)

PC: FIBRIC ACID DERIVATIVE

HOW IT WORKS: helps decrease the amount of fatty substances in your blood and increase good cholesterol HDL, it works by speeding up the natural processes that remove cholesterol from the body
MOA: inhibits TG synthesis and stimulates HDL

C/I: Renal and hepatic dysfuntion, nursing, gallbladder disease

PT INFO:
take 4 hours after or 2 hours before a bile acid binding resin (lower LDL) [cholestyramine]
abdominal pain, diarrhea, constipation, nausea or rhinitis
avoid coumadin (anticoagulants) adjust INR for fenofibrate use if already on warfarin
myopathies-breakdown of muscle tissue-byproduct is dangerous to kidneys- muscle soreness, achiness report

ATORVASTATIN (LIPITOR)
LOVASTATIN (MEVACOR)
PRAVASTATIN (PRAVACHOL)
ROSUVASTATIN (CRESTOR)
SIMVASTATIN (ZOCOR)

PC: HMG-COA REDUCTASE INHIBITOR

TC: HYPERLIPIDEMIA

category X [fetus requires lipids and this lipid blocks this medication from making lipids], active liver disease

PT. INFO
unexplained muscle pain, tenderness, or weakness
avoid grapefruit juice
concomitant antacid use - separate by 2 hours [Magnesium and calcium, example TUMS]
myopathies [ muscle soreness, tenderness, weakness]
alcohol may increase liver problems
DM- affect blood sugar
won't notice changes
lifestyle changes

C/I: hepatic dysfunction

EZETIMIBE

PC: CHOLESTEROL ABSORPTION INHIBITOR

TC: ANTIHYPERLIPIDEMIC

C/I: hepatic impairment (metabolized)/pregnancy C
PT. INFO
myopathies: breakdown of muscle tissue, muscle soreness, achiness
cholestyramine- take 4 hours before or 2 hours after
dizziness
if you are taking (ezetimibe, fenofibrate) before bile acid resin, take (E, F) then wait 2 hours and then take bile acid resin
AFTER: take bile acid resin wait 4 hours then take (E, F)

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