HBJ - Micro First Line
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Created by:
hannahbessejackson on June 20, 2012
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41 terms
Terms | Definitions |
|---|---|
 Rocky Mtn Spotted Fever | Doxycycline = tetracycline, fecal excretion (kidney disease) |
| Bowel surgery | neomycin |
| atypical PNA | erythromycin (macrolides) - mycoplasma, chlamydia, legionella |
| 1st and 2nd line neisseria gonorrhea | 1. ceftriaxone 2. macrolides - always treat for chlamydia as well (silent STD) using AZITHRO |
| chlamydia | 1. Doxycycline 2. Azithro (1 shot = inc. compliance; better for pregnancy) or 14d erythro children **OTHER MACROLIDES = roxithromycin, clarithromycin **Dont treat for gonorrhea as well if not seen on Gram stain, but DO tx for chlamydia if +gonorrhea d/t poorer staining + much higher prevalence *sulfas can also tx |
| Syphilis | Penicillin G (IV), V (po) |
| Lyme disease | 1. tetracycline (doxy) 2. ceftriaxone (3rd gen) |
| M. pneumoniae | erythromycin tetracycline (tetra, doxy, demeclo, mino) |
| Rickettsia | tetracyclines (tetra, doxy, demeclo, mino) *ability to ACCUMULATE INTRACELLULARLY gives particular advantage vs. rickettsial + chlamydial dz |
| Aspiration PNA | (e.g. ANAEROBES - bacteroides, clostridium perfringens) = clindamycin (lincomycin also a lincosamide) |
| Simple UTI | Sulfa (triple) or SMX |
| Nocardia | sulfas |
| Combination TMP-SMX used for which 3 bugs | Shigella Salmonella PCP (also for simple UTIs) |
| GNRs in UTI | fluoroquinolones |
| used with bismuth + amoxicillin/tetracycline for H. pylori | metronidazole |
| C. diff | metronidazole - can also use oral vanc (i think...) |
| antibacterial that also serves as antiprotozoal | metronidzaole - Giardia, entamoeba, trchomonas, gardnerella vaginalis, anaerobes (Bacteroides, C. diff) |
| anaerobic infection BELOW the diaphragm | metronidazole |
| anaerobic infection ABOVE diaphragm | clindamycin |
| M. tuberculosis | Ppx = INH Tx = RIPE Rifampin, Isoniazid, Pyrazinamide, Ethambutol |
| M. avium-intracellulare | Ppx = azithromycin (macrolide) Tx = Azithro, rifampin, ethambutol, streptomycin (rifampin + ethambutol = crossover drugs with M. TB) |
| M. leprae | NO ppx Dapsone, rifampin, clofazimine |
| delays resistance to dapsone given for leprosy | rifampin |
| meningococcal ppx + chemoppx in contacts of children with HiB | Rifampin |
| Ppx meningococcal infection | cipro (drug of choice) 2nd line = rifampin, minocycline |
| gonorrhea | ceftriaxone |
| syphilis | benzathine PCN G |
| H/o recurrent UTIs | TMP-SMX |
| Endocarditis w/ surgical or dental procedures | PCNs |
| Ppx PCP PNA | bactrim CD4<200 |
| Ppx PCP + toxoplasmosis | bactrim CD4<100 |
| Ppx against mycobacterium avium complex (MAC) | azithromycin CD4 <50 |
| MRSA | vancomycin |
| VRE | linezolid Streptogramins |
| Community-acquired PNA | macrolides |
| Hospital-acquired PNA | fluoroquinolones |
| ICU pneumonia | B-lactam+ (Fluoroquinolone OR azithromycin) |
| Actinomyces | Penicillin G Ampicillin *SNAP |
| Nocardia | Sulfas *SNAP |
| diptheria | penicillin or erythromycin |
| Viridans-group strep | Penicillin G (Subacute bacterial endocarditis a.w dental caries) *ALSO holds true for SBE seondary to: 1. S. Bovis (non-enterococci, gamma-hemolytic, bile SOLUBLE) - colon CA association 2. Enterococci (E. faecium/faecilus) - after GU procedure |
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